Results 191 to 200 of about 105,175,213 (210)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

More fundamental than the fundamental metallicity relation [PDF]

open access: yesAstronomy and Astrophysics
Context One of the most fundamental scaling relations in galaxies is observed between metallicity and stellar mass – the mass-metallicity relation (MZR) – although recently a stronger dependence of the gas-phase metallicity with the galactic ...
Sebastian F Sanchez   +2 more
exaly   +2 more sources
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New fundamental relation and complete part of fuzzy hypermodules

Journal of Discrete Mathematical Sciences and Cryptography, 2022
Bijan Davvaz, Narjes Firouzkouhi
exaly  

On the fundamental relation used in nanoindentation with piecewisely defined indenters

Materials Science & Engineering A: Structural Materials: Properties, Microstructure and Processing, 2009
Guanghui Fu
exaly  

θ*-Relation on Hypermodules and Fundamental Modules Over Commutative Fundamental Rings

Communications in Algebra, 2008
Seid Mohammad Anvariyeh   +2 more
exaly  

Fundamental relation and automorphism group of very thinHv-groups

Communications in Algebra, 2017
Ali Reza Ashrafi, Mohammad Hamidi
exaly  

Fundamental relation on fuzzy hypermodules

Soft Computing, 2019
Bijan Davvaz, Narjes Firouzkouhi
exaly  

Effects of Assumed Pressure Distributions on the Fundamental Relation Used in Nanoindentation Data Analysis

International Journal of Mechanical Engineering Education, 2014
Guanghui Fu
exaly  

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