Results 61 to 70 of about 285,811 (242)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Revisiting the Fundamental Metallicity Relation with Observation and Simulation
The Astrophysical Journal LettersThe gas-phase metallicity of galaxies is regulated by multiple astrophysical processes, which makes it a crucial diagnostic of galaxy formation and evolution.
Chengyu Ma +9 more
doaj +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Journal of High Energy Physics, 2017 Recursion relations for the sphere 4-point and torus 1-point W3 $$ {\mathcal{W}}_3 $$ conformal blocks, generalizing Alexei Zamolodchikov’s famous relation for the Virasoro conformal blocks are proposed.
Rubik Poghossian
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The commutative quotient structure of m-idempotent hyperrings
Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2020 The α* -relation is a fundamental relation on hyperrings, being the smallest strongly regular relation on hyperrings such that the quotient structure R/α* is a commutative ring.
Zadeh Azam Adineh +2 more
doaj +1 more source
Teaching relational database fundamentals [PDF]
Proceedings of the 3rd Conference on Computing Education Practice, 2019 This paper describes and evaluates changes introduced in six successive\ud years teaching a relational databases module. We explain\ud how we plan to obtain some certainty on the value of interventions.\ud Using an archive of data over the period, we find some interventions\ud that should not be repeated.
openaire +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The Fundamental k-Form and Global Relations
Symmetry, Integrability and Geometry: Methods and Applications, 2008 In [Proc. Roy. Soc. London Ser. A 453 (1997), no. 1962, 1411-1443] A.S. Fokas introduced a novel method for solving a large class of boundary value problems associated with evolution equations.
Anthony C.L. Ashton
doaj