Results 151 to 160 of about 3,545,390 (309)
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker +14 more
wiley +1 more source
Representations of fundamental groups of algebraic manifolds and their restrictions to fibers of a fibration [PDF]
arXiv, 2000 We use pluriharmonic maps to study representations of fundamental groups of algebraic manifolds. This approach is functorial in the sense that the restriction of such a map to a fiber of a fibration remains pluriharmonic, and on this basis, we can investigate the relation between the properties of the original representation and what can be inferred by
arxiv
An analysis on the use of autoencoders for representation learning: Fundamentals, learning task case studies, explainability and challenges [PDF]
, 2020 David Charte +3 more
openalex +1 more source
Molecular Oncology, EarlyView.In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen +13 more
wiley +1 more source
Characters of fundamental representations of quantum affine algebras [PDF]
arXiv, 2005 We give closed formulae for the q-characters of the fundamental representations of the quantum loop algebra of a classical Lie algebra in terms of a family of partitions satisfying some simple properties. We also give the multiplicities of the eigenvalues of the imaginary subalgebra in terms of these partitions.
arxiv
Finite-temperature chiral transition in QCD with quarks in the fundamental and adjoint representation [PDF]
, 2005 Ettore Vicari +2 more
openalex +1 more source
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Molecular Oncology, EarlyView.Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha +6 more
wiley +1 more source
Applications of Surface Correlation to the Estimation of the Harmonic Fundamental of Speech
EURASIP Journal on Advances in Signal Processing, 2002 We present a method for estimating the fundamental frequency of harmonic signals, and apply this method to human speech. The method is based on cross-spectral methods, which provide accurate resolution of multicomponent FM signals in both time and ...
Nelson Douglas J
doaj +1 more source