Results 81 to 90 of about 249,079 (313)

Some remarks on the companions conjecture for normal varieties

Comptes Rendus. Mathématique
Drinfeld in 2010 proved the companions conjecture for smooth varieties over a finite field, generalizing L. Lafforgue’s result for smooth curves. We study the obstruction to prove the conjecture for arbitrary normal varieties.
D’Addezio, Marco
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Symmetric Wilson Loops beyond leading order

SciPost Physics, 2016
We study the circular Wilson loop in the symmetric representation of U(N) in $\mathcal{N} = 4$ super-Yang-Mills (SYM). In the large N limit, we computed the exponentially-suppressed corrections for strong coupling, which suggests non-perturbative ...
Xinyi Chen-Lin
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Lie algebras of Galois representations on fundamental groups [PDF]

Advanced Studies in Pure Mathematics, 2019
In this paper we are studying Lie algebras associated with Galoisrepresentations on the fundamental groups ofP1 ̄Q\({0,∞} ∪μ2n) andP1 ̄Q\({0,∞}∪μ3n)
openaire   +3 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Transfer of Media Characteristics among Dissimilar Media

Palabra Clave, 2017
A broad variety of media traits are transmedial in the sense that they can, to a certain extent, be transferred among media that differ in fundamental ways. This article presents a new theoretical framework for studying media transformation, which should
Lars Elleström
doaj  

Oscillator realisations associated to the D-type Yangian: Towards the operatorial Q-system of orthogonal spin chains

Nuclear Physics B, 2020
We present a family of novel Lax operators corresponding to representations of the RTT-realisation of the Yangian associated with D-type Lie algebras. These Lax operators are of oscillator type, i.e.
Rouven Frassek
doaj  

Fundamental Properties of Perturbation-Theoretical Integral Representations. II

Journal of Mathematical Physics, 1962
In the first part of this paper, it is investigated, apart from the perturbation-theoretical basis, under what conditions the perturbation-theoretical integral representations can be derived, and two theorems are given concerning this problem. In the second part, the asymptotic behavior of the weight function in the integral representation is ...
openaire   +6 more sources