Results 111 to 120 of about 269,891 (340)
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang+10 more
wiley +1 more source
A new challenge: the fundamental social rights [PDF]
Due to the current economic public condition, fundamental social rights are today condemned to be marginalized under the false accusation of implying unrealistic costs.
Luigi Di Santo
doaj
Protocol No. 11 to the Convention for the Protection of Human Rights and Fundamental Freedoms [PDF]
Peter Kempess
openalex +1 more source
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park+6 more
wiley +1 more source
PROTAGONISMO JUDICIAL NO BRASIL: em busca da concretização de direitos fundamentais sociais
This text makes an analysis about the each time more determinant acting of the Brazilian Judiciary to turn effective the fundamental social rights, attempting to comprehend this phenomenon, its causes and consequences.
Ana Teresa Silva de Freitas
doaj
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang+10 more
wiley +1 more source
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad+13 more
wiley +1 more source
question of the violation of human rights and fundamental freedom in any part of the world [PDF]
Mr Kamal Hossain, Special Rapporteur
openalex +1 more source
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran+16 more
wiley +1 more source