Results 121 to 130 of about 269,891 (340)

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

Molecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou, Aliki Ntzifa, Victoria Tserpeli, Ioanna Balgkouranidou, Alkistis Papatheodoridi, Evangelia Razis, Helena Linardou, Christos Papadimitriou, Amanda Psyrri, Flora Zagouri, Stylianos Kakolyris, Evi Lianidou   +11 more
wiley   +1 more source

Ativismo Judicial. Realidade Admissível Apenas para a Concretização dos Direitos Fundamentais Sociais

Revista Interdisciplinar de Direito, 2009
The central motivation of this article aims to identify the determinants of Ineff ec-tiveness of social rights and propose a solution to this problem consistent with the new constitutionalism based on the legalization of ...
Alfredo Canellas Guilherme da Silva
doaj  

Homelessness And The Issue of Freedom [PDF]

Journal of Constitutional Law, 2019
In this article the author explores the relationship between homelessness, the rules of public and private property, and the underlying freedom of those who are condemned by poverty to walk the streets and sleep in the open.
Jeremy Waldron
doaj  

Anti-abortion laws-the antithesis of the fundamental rights of women. [PDF]

Lancet Reg Health Eur, 2021
europepmc   +1 more source

Towards a Theory of Legal Animal Rights: Simple and Fundamental Rights. [PDF]

Oxf J Leg Stud, 2020
Stucki S.
europepmc   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

Molecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa, Zdenka Herudkova, Jan Hyl, Jakub Vlazny, Filip Sokol, Kvetoslava Matulova, Adam Folta, Jakub Hynst, Lucy Vojtova, Leos Kren, Martin Repko, Zdenek Racil, Jiri Mayer, Martin Culen   +13 more
wiley   +1 more source

Immunity passports, fundamental rights and public health hazards: a reply to Brown et al. [PDF]

J Med Ethics, 2020
de Miguel Beriain I, Rueda J.
europepmc   +1 more source

A combinatorial genesis of the right-angled relations in Artin's classical braid groups [PDF]

arXiv
We show that the fundamental group of unlabelled configuration spaces of thick particles in either a width-2 infinite strip or a width-2 rectangle are right-angled Artin groups capturing the right-angled essence of Artin's braid groups.
arxiv  

Transformation or Dilution: Fundamental Rights in the EU Social Space [PDF]

, 2006
Sandra Fredman
openalex   +1 more source

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

Molecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock, Lina Benzien, Sandra Lange, Maja Huehns, Alexandra Runge, Catrin Roolf, Anett Sekora, Gudrun Knuebel, Hugo Murua Escobar, Christian Junghanss, Anna Richter   +10 more
wiley   +1 more source