Results 231 to 240 of about 269,891 (340)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Advancing sexual health and well-being for all. [PDF]

Bull World Health Organ
Singh S, Tandon S, Esiet UU, Kågesten AE, Gruskin S, Shaikat SM, Bain LE, El Kak F, Logie CH, RamPrakash R, Freitas da Silveira M, Kumru R, Stardust Z, Turk T, Rubio-Aurioles E, Crone ET, Troussier T.   +16 more
europepmc   +1 more source

Utilizing Artificial neural networks (ANN) to regulate Smart cities for sustainable Urban Development and Safeguarding Citizen rights. [PDF]

Sci Rep
Kuang Z, Su J, Latifian A, Eshraghi S, Ghafari A.   +4 more
europepmc   +1 more source

The Consequences of the “Constitutionalization” of the Charter of Fundamental Rights of the European Union

, 2014
Maria-Luiza Hrestic
openalex   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Why the European Journal of Public Health and EUPHA are opposing President Trump's attack on the language of diversity. [PDF]

Eur J Public Health
Allebeck P, Albreht T, Marchandise C, McKee M.   +3 more
europepmc   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source

Profit shifting from Nigeria to Europe: The impact on human rights. [PDF]

PLOS Glob Public Health
Etter-Phoya R, Murray S, Hall S, Masiya M, O'Hare B.   +4 more
europepmc   +1 more source

Fundamental rights in the reasoning of Judge Cunha Rodrigues

, 2014
José Manuel Cabrita Vieira e Cunha
openalex   +2 more sources

A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers

FEBS Open Bio, EarlyView.
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei, Amir Barzegar Behrooz, Marco Cordani, Mahmoud Aghaei, Negar Azarpira, Daniel J. Klionsky, Saeid Ghavami   +6 more
wiley   +1 more source