Results 241 to 250 of about 269,891 (340)
The Emergence of AI in Public Health Is Calling for Operational Ethics to Foster Responsible Uses. [PDF]
Chassang G, Béranger J, Rial-Sebbag E.
europepmc +1 more source
Establishment and biological characterization of radioresistant colorectal cancer cell lines
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu+10 more
wiley +1 more source
Reform of agricultural land property rights system and grain production resilience: Empirical evidence based on China's "Three Rights Separation" reform. [PDF]
Wei Z, Peng J, Zhao Y, Li X, Wang C.
europepmc +1 more source
Measuring AMP‐activated protein kinase (AMPK) activity in vitro is crucial for testing AMPK activators or inhibitors with therapeutic potential. Here, we report an enzyme‐linked immunosorbent assay (ELISA)‐based AMPK activity assay with simple steps and high sensitivity, which offers a simple, robust, and cost‐effective alternative to traditional ...
Trezze P. Nguyen, Shangze Lyu, Yang Liu
wiley +1 more source
Representing Animals: Moral and Epistemic Limits for Protection Against Cruelty. [PDF]
Cordeiro-Rodrigues L, Duan D.
europepmc +1 more source
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel+13 more
wiley +1 more source
The contemporary challenge for ethical research involving the knowledge of indigenous peoples and local communities and afro-descendants and other marginalized, minority, or minoritized groups. [PDF]
Albuquerque UP+2 more
europepmc +1 more source
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui+15 more
wiley +1 more source