Results 261 to 270 of about 3,343,586 (362)

THE PRINCIPLE OF THE HIGHEST LEVEL OF PROTECTION: ANALYSIS OF ARTICLE 53 OF THE CHARTER OF FUNDAMENTAL RIGHTS OF THE EUROPEAN UNION IN THE LIGHT OF THE MELLONI JUDGMENT [PDF]

, 2014
Pedro Miguel Alves Ribeiro Correia, Inês Oliveira   +1 more
openalex  

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

Supporting Communication Access of People With Communication Disabilities and Communication Differences in UNCRPD-Ratified Countries: An Integrative Review. [PDF]

Int J Lang Commun Disord
Kearns Á, Jagoe C, Stockdale R, Clarke D, Manning M, Menamin RM, Fitzmaurice Y, Green J, Duffy O, Kelly H.   +9 more
europepmc   +1 more source

Realization and protection of the rights of workers as fundamentals of legal policy in the sphere of work

, 2015
Yu O Almaeva
openalex   +2 more sources

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Few rights, great threats, endless struggles: setbacks and resistance in the last decade of fights for legal abortion in Brazil. [PDF]

Sex Reprod Health Matters
Cardoso NM, Pércia Namé de Souza Franco M, Magalhães Cadioli L, Pires Lucas d'Oliveira AF, Meloni Vieira E.   +4 more
europepmc   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Preserving medical confidentiality in Brazilian criminal investigation cases: a narrative review of the principles of bioethics. [PDF]

Clinics (Sao Paulo)
Zarpellon HM, Bianchi F, Fürst H, Nunes R.   +3 more
europepmc   +1 more source

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

FEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson, Lisa Lif, Husam Oda, Alexandra Lorenzzi de Melo, David Lindquist, Håkan Hedman   +5 more
wiley   +1 more source

Realizing human rights in rural Punjab of India: a study of enforcement of selected human rights. [PDF]

Front Sociol
Pathak P, Nandini V, Yadav D, Kaur S, Sen RK, Riang S.   +5 more
europepmc   +1 more source