Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Multisystemic resilience to shocks: a temporal analysis of health, fundamental rights and freedoms, and economic resilience during the first wave of the COVID-19 pandemic in 22 European countries. [PDF]
BMJ Open, 2023 Clausin M +6 more
europepmc +1 more source
Gröbner--Shirshov bases for Vinberg--Koszul--Gerstenhaber right-symmetric algebras [PDF]
Fundamental and Applied Mathematics, 14(8)(2008), 55-67. (in
Russian), 2009 In this paper, we establish the Composition-Diamond lemma for right-symmetric algebras. As an application, we give a Gr\"{o}bner-Shirshov basis for universal enveloping right--symmetric algebra of a Lie algebra.
arxiv
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker +14 more
wiley +1 more source
Fundamental rights and the implementation of a bill of rights in South Africa1
Koers : Bulletin for Christian Scholarship, 1989 In the title of this article reference is made to fundamental rights and not human rights because it is my contention that human rights should be seen as only one category of fundamental rights.
P. J. van Niekerk
doaj +1 more source
The Disposal of COVID-19 Dead Bodies: Impact of Sri Lanka's Response on Fundamental Rights. [PDF]
J Hum Rights Pract, 2021 Marsoof A.
europepmc +1 more source
Molecular Oncology, EarlyView.In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen +13 more
wiley +1 more source
The need for global safeguards for fundamental rights of children at risk of infant oral mutilation (IOM). [PDF]
BMJ Glob Health, 2022 Kemoli AM, Sidhu SK, Cheng L.
europepmc +1 more source
Graph eigenvectors, fundamental weights and centrality metrics for nodes in networks [PDF]
arXiv, 2014 Several expressions for the $j$-th component $\left( x_{k}\right)_{j}$ of the $k$-th eigenvector $x_{k}$ of a symmetric matrix $A$ belonging to eigenvalue $\lambda_{k}$ and normalized as $x_{k}^{T}x_{k}=1$ are presented. In particular, the expression \[ \left( x_{k}\right)_{j}^{2}=-\frac{1}{c_{A}^{\prime}\left( \lambda_{k}\right) }\det\left( A_ ...
arxiv