REMARKS ON THE METROPOLITAN HOSPITAL SUNDAY FUND: Delivered at the Mansion House on the occasion of the Hospital Sunday Fund Presenting to the Mansion House a Bust of the late Mr. George Herring [PDF]
Heather Morris
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Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
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Resident funding and care home quality: a retrospective observational analysis of the impact of the two-tier care system in England. [PDF]
Bach-Mortensen A+3 more
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R.A.M.C. FUND AND R.A.M.C. OFFICERS' BENEVOLENT SOCIETY. [PDF]
E.M. Wilson
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The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh+6 more
wiley +1 more source
Expression of concern for global biomedical research by the human genome organization (HUGO). [PDF]
Hamosh A+12 more
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Further Education Funding Council : circular 00/29 : funding : final funding unit return [PDF]
core
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
Inequity of NIH cancer funding in the United States: an ecological study predicting funding based on disease burden from 2008 through 2023. [PDF]
Berglas E+5 more
europepmc +1 more source