Results 41 to 50 of about 5,999,713 (315)

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Contribution of NIH funding to new drug approvals 2010–2016

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance This report shows that NIH funding contributed to published research associated with every one of the 210 new drugs approved by the Food and Drug Administration from 2010–2016.
Ekaterina Galkina Cleary, J. Beierlein, Navleen Surjit Khanuja, Laura M. McNamee, F. Ledley   +4 more
semanticscholar   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

Opportunistic offer of human papillomavirus (HPV) self-testing in ethnically diverse primary care clinics in Aotearoa New Zealand: an implementation study

BMC Primary Care
Background Human papillomavirus (HPV) self-testing was introduced in Aotearoa New Zealand in September 2023, with the potential to improve screening access and reduce inequities for priority populations: Māori, Pacific, and those overdue for screening by 
Karen Bartholomew, Lily P. H. Yang, Cleo Neville, Anna Maxwell, Phyu Sin Aye, Jane Grant, Collette Bromhead, Georgina McPherson, Kate Moodabe, Richard Massey, Sue Crengle, Susan M. Sherman, Nina Scott, Pania Coote, Wendy Burgess, Deralie Flower, Jyoti Kathuria   +16 more
doaj   +1 more source

Carved in stone

Documenta Praehistorica
The late 3rd millennium BC petrification phenomenon in southern Portugal challenges traditional interpretations, and invites us to explore the complex interplay between prehistoric memory and identity.
Ana Catarina Basílio
doaj   +1 more source

Associations of topic-specific peer review outcomes and institute and center award rates with funding disparities at the National Institutes of Health

eLife, 2021
A previous report found an association of topic choice with race-based funding disparities among R01 applications submitted to the National Institutes of Health (‘NIH’) between 2011 and 2015.
Michael S Lauer, Jamie Doyle, Joy Wang, Deepshikha Roychowdhury   +3 more
doaj   +1 more source

Contest models highlight inherent inefficiencies of scientific funding competitions [PDF]

PLoS Biology, 2018
Scientific research funding is allocated largely through a system of soliciting and ranking competitive grant proposals. In these competitions, the proposals themselves are not the deliverables that the funder seeks, but instead are used by the funder to
K. Gross, Carl T. Bergstrom
semanticscholar   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

The role of community pharmacies in the provision of human papillomavirus (HPV) self-testing: A range of delivery models and proof-of-concept study

Exploratory Research in Clinical and Social Pharmacy
Background: Cervical cancer persists in Aotearoa New Zealand, mainly due to under-screening. Longstanding disparities in screening and cancer rates remain for Māori, Pacific and people not regularly screened.
Karen Bartholomew, Lily P.H. Yang, Cleo Neville, Anna Maxwell, Joanna Hikaka, Jane Grant, Collette Bromhead, Georgina McPherson, Kate Moodabe, Richard Massey, Sue Crengle, Susan M. Sherman, Nina Scott, Pania Coote, Wendy Burgess, Deralie Flower, Jyoti Kathuria   +16 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source