Results 81 to 90 of about 1,789,855 (310)

Aboriginal-mainstream partnerships: exploring the challenges and enhancers of a collaborative service arrangement for Aboriginal clients with substance use issues

BMC Health Services Research, 2013
Background Partnerships between different health services are integral to addressing the complex health needs of vulnerable populations. In Australia, partnerships between Aboriginal1 community controlled and mainstream services can extend health care ...
Taylor Kate P, Bessarab Dawn, Hunter Lorna, Thompson Sandra C   +3 more
doaj   +1 more source

Factors affecting effective community participation in maternal and newborn health programme planning, implementation and quality of care interventions. [PDF]

, 2017
BACKGROUND: Community participation in in health programme planning, implementation and quality improvement was recently recommended in guidelines to improve use of skilled care during pregnancy, childbirth and the postnatal period for women and newborns.
Howard-Grabman, Lisa, Marston, Cicely, Miltenburg, Andrea Solnes, Portela, Anayda   +3 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Understanding the organization and delivery of health services following the repatriation of South Sudanese refugees from the West Nile districts in Uganda

Conflict and Health
Background Low- and middle-income countries face several challenges in providing health services, particularly to displaced populations, during all phases of emergencies.
Henry Komakech, Lynn Atuyambe, Fadi El-Jardali, Christopher Garimoi Orach   +3 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

The financing of stand-alone palliative Care Services in Uganda: analysis of the implications for sustainability

BMC Palliative Care, 2019
Background Sustainable funding is key for ensuring the quality and coverage of palliative care services. This study examined the sources of funding for stand-alone palliative care services in Uganda as well as their services financial sustainability ...
Jacinto Amandua, Melkizedeki Stephen Kimaro, Eddie Mwebesa, Ivan Mugisha Taremwa, Christine Atuhairwe   +4 more
doaj   +1 more source

Project Retrosight. Understanding the returns from cardiovascular and stroke research: Policy Report [PDF]

, 2011
Copyright @ 2011 RAND Europe. All rights reserved. The full text article and the summary of the article are both available via the links below.This project explores the impacts arising from cardiovascular and stroke research funded 15-20 years ago and ...
Buxton, MJ, Grant, J, Hanney, S, on behalf of the Project Retrosight Team, Pollitt, A, Wooding, S   +5 more
core  

Project Retrosight. Understanding the returns from cardiovascular and stroke research: Case Studies [PDF]

, 2011
Copyright @ 2011 RAND Europe. All rights reserved. The full text article is available via the link below.This project explores the impacts arising from cardiovascular and stroke research funded 15-20 years ago and attempts to draw out aspects of the ...
Buxton, MJ, Grant, J, Hanney, S, Pollitt, A, Wooding, S   +4 more
core  

Using a realist approach to evaluate smoking cessation interventions targeting pregnant women and young people [PDF]

, 2010
Background This paper describes a study protocol designed to evaluate a programme of smoking cessation interventions targeting pregnant women and young people living in urban and rural locations in Northeast Scotland.
A Coote, A Kubisch, A Tannahill, AL Strauss, Ash Scotland, BMRB Social Research, C Pope, D Nutbeam, Denise A Gray, E Pound, E Roddy, E Van Teijlingen, E Wimbush, Edwin R van Teijlingen, Flora CG Douglas, H Connelly, I Rootman, ISD Scotland, J Green, J Owen, J Ritchie, JP Connell, JW Cresswell, K Judge, K Tones, K Tones, L Bonner, L Rychetnik, MP Kelly, N McCurry, NHS Health Scotland and ASH Scotland, NHS Health Scotland and ASH Scotland, NHS National Institute for Health and Clinical Excellence, NHS National Institute for Health and Clinical Excellence, NHS National Patient Safety Agency, P Craig, R Pawson, RE Glasgow, RL Murray, S MacDonald, S Sridharan, Scottish Executive, Scottish Executive, SJ Haw, TA Abma, W Gnich, WK Kellogg, World Health Organisation, Y Wadsworth   +48 more
core   +4 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source