Results 41 to 50 of about 13,927 (162)

Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed, Supreet S. Randhawa, Jason H. Peragallo, Prabhumallikarjun Patil, Grace Gombolay, Varun Kannan   +5 more
wiley   +1 more source

Addressing the 'forgotten art of fundoscopy': evaluation of a novel teaching ophthalmoscope

, 2016
Background: Direct ophthalmoscopy is an essential skill that students struggle to learn. A novel 'teaching ophthalmoscope' has been developed that allows a third person to observe the user's view of the fundus.
E Tamsett (16240664), Claire Smith (4464775), J Moore (6981110), D Hassan (16240661), C Schulz (13311093)   +4 more
core   +2 more sources

C3 glomerulopathy associated with peripheral retinal drusen: Case report and review of the literature

Indian Journal of Ophthalmology. Case Reports
A 46-year-old female was admitted with complaints of fever and generalized bodily swelling and a working phenotypic diagnosis of nephrotic syndrome. Renal function was mildly impaired.
Salil Mehta, Juhi Bhargava, Hemant Mehta
doaj   +1 more source

Real‐world insights on switching aflibercept dosage for enhanced outcomes in age‐related macular degeneration (RISE‐AMD): Safety data

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate real‐world safety experience with aflibercept 8 mg in a large case series of patients with neovascular age‐related macular degeneration (nAMD). Methods Due to a high proportion of patients on short treatment intervals, patients with nAMD at a Danish tertiary retina clinic were systematically switched to aflibercept 8 mg ...
Mary Graciya Karunainathan, Celine Lee, Kaweh Daniel Zohalinejad, Mads Odgaard Mæng, Nanna Würtz Fabrin, Sigurrós Jónsdóttir, Anne Kjærsgaard Hassing, Søren Kveiborg Yde, Charles C. Wykoff, Henrik Vorum, Yousif Subhi, Marie Ørskov, Lasse Jørgensen Cehofski   +12 more
wiley   +1 more source

A Prospective Audit Comparing Optos Widefield Imaging to Fundus Examination for Von Hippel-Lindau Retinal Screening [PDF]

, 2022
Background Von Hippel-Lindau (VHL) disease is an autosomal dominant multisystem disorder caused by germline mutations at chromosome 3p25-26 in the VHLtumour suppressor gene.
Al-Khuzaei, Saoud, Lim, Ernest, Downes, Susan, Iqbal, Naeem, Stahl, Matthew, Jones, Rebecca, Halliday, Dorothy   +6 more
core   +1 more source

Clinical manifestations of dual‐gene variants in retinitis pigmentosa

Acta Ophthalmologica, EarlyView.
Abstract Purpose Retinitis pigmentosa (RP) is an inherited retinal disease (IRD), whereby each affected individual typically harbours pathogenic variants in a single causative gene, yet the disorder exhibits marked genetic heterogeneity, with more than 100 genes reported to underlie RP.
Lasse Wolfram, Jan‐Philipp Bodenbender, David A. Merle, Milda Reith, Anton Sonntag, Krunoslav Stingl, Tobias B. Haack, Theresia Zuleger, Bernd Wissinger, Laura Kühlewein, Katarina Stingl, Susanne Kohl   +11 more
wiley   +1 more source

Topological Data Analysis for Eye Fundus Image Quality Assessment

Diagnostics, 2021
The objective of this work is to perform image quality assessment (IQA) of eye fundus images in the context of digital fundoscopy with topological data analysis (TDA) and machine learning methods. Eye health remains inaccessible for a large amount of the
Gener José Avilés-Rodríguez, Juan Iván Nieto-Hipólito, María de los Ángeles Cosío-León, Gerardo Salvador Romo-Cárdenas, Juan de Dios Sánchez-López, Patricia Radilla-Chávez, Mabel Vázquez-Briseño   +6 more
doaj   +1 more source

Retinal dystrophies simulating geographic atrophy: A diagnostic challenge

Acta Ophthalmologica, EarlyView.
Abstract Geographic atrophy (GA) is the chronic loss of retinal pigment epithelium, photoreceptors and choriocapillaris, marking the dry late stage of age‐related macular degeneration (AMD). GA prevalence is expected to rise in the upcoming decades. Advanced GA leads to central scotomas, reducing visual acuity and quality of life, potentially resulting
Johanna M. Colijn, Frank G. Holz, Jeroen Pas, Carel Hoyng   +3 more
wiley   +1 more source

Smartphone fundoscopy. [PDF]

, 2012
5 ROP retinal detachment after bevacizumab monotherapy.Indeed, we have detected a new retinal detachment as late as72 weeks PMA. We speculate that the anti-VEGF treatmentwas inadequately effective in these cases because the dos-age did not match the load
Bastawrous, Andrew, Andrew Bastawrous
core   +1 more source

Kcnv2 E151X Mouse Captures Hallmarks of KCNV2‐Associated Retinal Dystrophy

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background KCNV2‐associated retinopathy is a rare inherited retinal dystrophy caused by variants in the KCNV2 gene, leading to disrupted photoreceptor behaviour and progressive deterioration of vision. Patients have characteristic electroretinography abnormalities, including reduced cone response, delayed and reduced rod response to low light ...
Nermina Xhaferri, Sumit Biswas, Benjamin Davies, Moritz Lindner   +3 more
wiley   +1 more source