Results 31 to 40 of about 23,437 (167)

Retinal vasculitis: An update with our experience

TNOA Journal of Ophthalmic Science and Research, 2021
Retinal vasculitis is a sight-threatening inflammatory condition affecting the retinal vessels. It can occur due to several etiologies and spectrum of other ocular inflammatory conditions.
Jyotirmay Biswas, Nipun Bagrecha, Puja Maitra   +2 more
doaj   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Susac's syndrome: the value of fundus fluorescein angiography [PDF]

BMJ Case Reports, 2014
A 19-year-old woman presented with a 4-week history of headache, ataxia, vertigo, confusion, intermittent blurred vision in the right eye and intermittent hearing loss. MRI revealed white matter lesions and ‘pepper pot’ lesions of the corpus callosum. The cerebrospinal fluid had raised protein and lymphocytes.
Imran Joseph, Khan, Holger, Allroggen, Sergio, Pagliarini   +2 more
openaire   +2 more sources

Manual of Fundus Fluorescein Angiography [PDF]

Archives of Ophthalmology, 1991
The author's stated purpose is to provide "a detailed and comprehensive account of fluorescein angiographic findings of retinal disorders." He has assembled a collection of beautiful color photographs and fluorescein angiograms for this concise volume.
openaire   +2 more sources

Microglial TSPAN4‐Dependent Migrasomes Promote Pathological Retinal Neovascularization via Immune‐Vascular Crosstalk

Advanced Science, EarlyView.
Combined high‐glucose and hypoxic stress switches microglia into a TSPAN4‐dependent migrasome‐producing state. These migrasomes deliver pro‐angiogenic signals to endothelial cells, activating HIF‐1α/VEGF signaling, disrupting vascular junctions, and fueling pathological neovascularization. This work uncovers migrasome‐mediated immune‐vascular crosstalk
Jingyi Xu, Jingfan Wang, Pengfei Ge, Qinyuan Gu, Hongying Li, Yuanyuan Fan, Haiyue Xie, Yangyang Lu, Yifan Lin, Xinjing Wu, Chengkun Wang, Ping Xie, Zizhong Hu   +12 more
wiley   +1 more source

Systemic Diseases and the Eye: A Translational Perspective on Diabetes

Chronic Diseases and Translational Medicine, EarlyView.
The eye–brain–cardiometabolic axis in diabetes: retinal biomarkers as indicators of systemic disease. ABSTRACT Diabetes mellitus is a global chronic disease that affects the whole body and not just glucose metabolism. In diabetes, non‐invasive ocular changes can help understand microvascular, neurodegenerative, and inflammatory processes. This analysis
Matteo Capobianco, Marco Zeppieri, Simonetta Gaia Nicolosi, Niccolò Castellino, Francesco Cappellani, Irene Gattazzo, Caterina Gagliano   +6 more
wiley   +1 more source

Fundus fluorescein angiography and OCT [PDF]

Graefe's Archive for Clinical and Experimental Ophthalmology, 2010
Dear Editor, Gallego-Pinazo and associates [1] raise an interesting point, questioning to the continued need for fundus fluorescein angiography (FFA) in the current era of optical coherence tomography (OCT) for retinal vascular pathologies. They correctly point out that FFA is an invasive investigation associated with the potential for side-effects ...
openaire   +1 more source

Artificial Intelligence in Ophthalmology: From Methodological Advances to Clinical Translation and Future Directions

Eye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) is reshaping ophthalmology from task‐specific image analysis toward multimodal, longitudinal, and clinically integrated decision support. This narrative review summarizes the methodological evolution of ophthalmic AI, including traditional machine learning, task‐specific deep learning, self‐supervised learning ...
Yuxin Liu, Hanruo Liu
wiley   +1 more source

Multimodal Imaging in AIDS-Related Ocular Cryptococcosis

Case Reports in Ophthalmological Medicine, 2021
Purpose. To report multimodal imaging findings in two cases of AIDS-related cryptococcal chorioretinitis associated with uveitis and vasculitis. Methods.
Maria Fernanda Flores Herrera, Nicolas Dauby, Evelyne Maillart, Agnes Libois, Alberto Papaleo, Hind El Ouardighi, Laurence Postelmans, François Willermain, Dorine Makhoul   +8 more
doaj   +1 more source

Real‐world incidence and clinical characteristics of intraocular inflammation following intravitreal faricimab therapy: A safety study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To estimate the real‐world incidence of intraocular inflammation (IOI) following intravitreal faricimab injections at a large, highly specialized tertiary centre. Methods Single‐centre, retrospective cohort study with chart review using an electronic injection database and electronic medical records from November 2023 to August 2024 ...
Miklos Schneider, Leyla Turan, Farah Arif, Jakob Bjerager, Oliver Niels Klefter, Carsten Faber, Yousif Subhi, Javad Nouri Hajari   +7 more
wiley   +1 more source