Results 111 to 120 of about 501,516 (209)

A health economic pilot study comparing two diabetic retinopathy screening strategies

Scientific Reports
To compare two screening strategies for diabetic retinopathy (DR), and to determine the health-economic impact of including optical coherence tomography (OCT) in a regular DR screening. This cross-sectional study included a cohort of patients (≥ 18 years)
Ellen Steffenssen Sauesund, Silvia N. W. Hertzberg, Øystein Kalsnes Jørstad, Morten Carstens Moe, Maja Gran Erke, Dag Sigurd Fosmark, Goran Petrovski   +6 more
doaj   +1 more source

Decellularised Corneal Stromal Lamina With or Without Autologous Adipose‐Derived Adult Stem Cells for Advanced Keratoconus: 1‐Year Results of a Phase I/IIa Clinical Trial

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To report the 1‐year clinical outcomes of decellularised human corneal stromal lamina implantation, with or without autologous adipose‐derived adult stem cells (ADASCs), for advanced keratoconus in a European cohort. Methods In this prospective, randomised Phase I/IIa trial, 10 eyes of 10 patients were allocated to decellularised ...
Hao Zhang, Jorge L. Alió del Barrio, Alejandra E. Rodriguez, Rafael I. Barraquer, Francisco Arnalich‐Montiel, David Mingo‐Botín, María Eugenia Fernández Santos, Jorge L. Alió   +7 more
wiley   +1 more source

CRB1‐Associated Inherited Retinal Dystrophies: Prospective Natural History Study With 4 Years of Follow‐Up

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background The lack of validated and sensitive clinical endpoints remains a major challenge in the design of gene therapy trials for inherited retinal dystrophies (IRDs). This prospective longitudinal cohort study describes the natural disease progression of IRDs caused by pathogenic mutations in the Crumbs homologue 1 (CRB1) gene, and ...
Jessica S. Karuntu, Xuan‐Thanh‐An Nguyen, Mays Talib, Mary J. van Schooneveld, Jan Wijnholds, Maria M. van Genderen, Jos Twisk, Nicoline E. Schalij‐Delfos, Caroline C. W. Klaver, Ralph J. Florijn, Jacoline B. ten Brink, Magda A. Smoor, L. Ingeborgh van den Born, Carel B. Hoyng, Alberta A. H. J. Thiadens, Camiel J. F. Boon   +15 more
wiley   +1 more source

Randomised Clinical Trial to Evaluate the Efficacy of Acetazolamide for the Treatment of Cystoid Fluid Collections in X‐Linked Retinoschisis: The AXIS Trial

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background This trial aimed to evaluate the efficacy of oral acetazolamide in reducing cystoid fluid collections (CFC) and improving visual function in patients with X‐linked retinoschisis (XLRS). Methods In this investigator‐initiated, single centre, open‐label, randomised controlled trial, XLRS patients aged ≥ 12 years with fovea‐involving ...
Jonathan Hensman, Hind Almushattat, Roselie M. H. Diederen, Tien‐En Tan, Peilun Dai, Coen de Vente, Daniel S. W. Ting, Maria M. van Genderen, Jeannette Ossewaarde‐van Norel, Redmer van Leeuwen, Martha J. H. Tjon‐Fo‐Sang, Clara I. Sánchez, M. Dominik Fischer, Maximilian Pfau, Jos W. R. Twisk, Camiel J. F. Boon   +15 more
wiley   +1 more source

Feasibility and quality of nonmydriatic fundus photography in children

, 2011
Ocular funduscopic examination is difficult in young children and is rarely attempted by nonophthalmologists. Our objective was to determine the feasibility of reliably obtaining high-quality nonmydriatic fundus photographs in children.
Bruce, Beau B, Valérie Biousse, Cédric Lamirel, Daniela Toffoli, Nancy J. Newman, Lamirel, Cédric, Henderson, Amanda D, Newman, Nancy J, Amanda D. Henderson, Toffoli, Daniela, Biousse, Valérie, Beau B. Bruce   +11 more
core   +1 more source

Correcting Axial Length‐Related Magnification Errors in Optical Coherence Tomography Angiography Improves Machine Learning Classification Performance in High Myopia

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To determine whether axial length‐related magnification correction in optical coherence tomography angiography (OCTA) improves machine learning classification of high myopia and resolves inconsistencies in the values and discriminatory power of OCTA microvascular metrics.
Danuta M. Sampson, Mila Yue Zhang, Hemn Baghban Jaldian, Madeleine S. Torcasso, Gavrielle R. Untracht, Jocelyn J. Drinkwater, Mei Zhao, David D. Sampson, Andrew Lam, Fred K. Chen   +9 more
wiley   +1 more source

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

Cell Proliferation, EarlyView.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu, Yanan Guo, Kangjian Xiang, Shuyi Wang, Dongchang Xiao, Mengqing Xiang   +5 more
wiley   +1 more source

Ultra-Widefield Fundus Autofluorescence Findings as an Indicator of Duration in Rhegmatogenous Retinal Detachment

Ophthalmology Science
Objective: To describe and compare characteristics of rhegmatogenous retinal detachments (RRDs) on ultra-widefield (UWF) color fundus photography versus UWF fundus autofluorescence (FAF). Design: A retrospective observational study.
David L. Zhang, MD, Isaac Bakis, BS, Russel H. Dinh, MD, Megan S. Steinkerchner, MD, Avni P. Finn, MD, MBA   +4 more
doaj   +1 more source

Ocular Fundus Photography

, 2018
Overview of the various ocular fundus cameras and how they are used, including: Digital mydriatic tabletop fundus camera, Digital nonmydriatic table top fundus camera, Digital handheld nonmydriatic fundus camera and the Smartphone handheld fundus ...
Devin Mackay, MD
core  

Vertigo and dizziness syndromes in children and adolescents: Clinical presentation and diagnostic pathway

Developmental Medicine &Child Neurology, EarlyView.
This study characterized 519 children and adolescents with vertigo using clinical, diagnostic, imaging, quality‐of‐life, and demographic data, identifying vestibular migraine as the most frequent diagnosis, followed by functional dizziness and recurrent vertigo of childhood.
Doreen Huppert, Ralf Strobl, Andreas Zwergal, Florian Heinen, Michaela V. Bonfert, Marius Näher, Anna Huppert, Filipp M. Filippopulos   +7 more
wiley   +1 more source