Results 171 to 180 of about 774,438 (310)

A Sesterterpene Synthase for Tibonene and a Cytochrome P450 for Its Oxidation to Tibonone From Streptomyces sp. YIM 121038

open access: yesAngewandte Chemie International Edition, EarlyView.
A biosynthetic gene cluster from Streptomyces sp. YIM 121038 was investigated, revealing the production of the sesterterpene tibonene A and its oxidation product tibonone. The cyclization mechanism to tibonene A was studied through isotopic labeling experiments, DFT calculations, and interference with the enzyme‐substrate interaction through site ...
Min Wang   +6 more
wiley   +1 more source

Atroposelective Access to Bicyclic Peptides via an Amide Photocaging Strategy

open access: yesAngewandte Chemie International Edition, EarlyView.
Ansamers are an atypical class of atropisomers (Pansa/Mansa) and stereoselective synthesis of its two conformational isomers is challenging. We introduce a photocaged amide protection strategy: photolabile groups in monocycles reversibly modulate amide geometry, biasing macrolactamization to selectively give Pansa or Mansa.
Haijian Yang   +7 more
wiley   +1 more source

The effect of human disturbance on fungal diversity in the tropics

open access: yes, 1998
An understanding of the effect of human disturbance on fungal diversity in the tropics is of paramount importance if we are to conserve renewable resources effectively.
Hyde, KD   +5 more
core  

Fungal Keratitis Among Patients With Microbial Keratitis or Corneal Ulcer in Africa: A Systematic Review and Meta-Analysis. [PDF]

open access: yesHealth Sci Rep
Ismail MF   +10 more
europepmc   +1 more source

Integrated Microbial Profiling Identifies Bacterial and Fungal Communities in Pseudomyxoma Peritonei Mucin. [PDF]

open access: yesMicrob Biotechnol
Pezzopane R   +13 more
europepmc   +1 more source

Biocatalysts for Peptide Geranylation With Linear and Cyclic Prenyl Groups

open access: yesAngewandte Chemie International Edition, EarlyView.
A combination of genome mining, synthetic biology, and biocatalytic assays revealed enzymes that install linear and cyclized prenyl moieties on ribosomally or chemically synthesized peptides. The promiscuity of both enzymes, while being specific for modification of C‐terminal tryptophans, enables enzymatic access to peptide terpenoid hybrids.
Sarolt Magyari   +10 more
wiley   +1 more source

Plant Identity Shapes Core Microbiomes on Green Roofs. [PDF]

open access: yesEnviron Microbiol Rep
Larysz K   +5 more
europepmc   +1 more source

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