Results 211 to 220 of about 363,639 (294)

Endoplasmic reticulum stress and the unfolded protein response in lung diseases: molecular pathways and therapeutic interventions

open access: yesThe Journal of Pathology, EarlyView.
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song   +6 more
wiley   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde   +4 more
wiley   +1 more source

The dual role of sertraline: From antidepressant to antifungal drug with broad metabolic disruption. [PDF]

open access: yesGenet Mol Biol
Azevedo MIG   +5 more
europepmc   +1 more source

Migrasomes, Matrix‐Bound Nanovesicles, and More: Messengers in the Matrix

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) and particles (EPs) are diverse micro‐ and nanoparticles that circulate in bodily fluids and can attach to, or be deposited onto, the extracellular matrix (ECM) and other surfaces. To date, the nomenclature and classification of matrix‐bound or matrix‐associated EVs and EPs (MEVPs) have been unclear, largely due to
Anna V. Kolesov   +3 more
wiley   +1 more source

Metabarcoding Reveals Rich and Diverse Aeromycobiota in Protected Oak Forests. [PDF]

open access: yesMicrob Ecol
Lygis V   +4 more
europepmc   +1 more source

Life after herbarium digitisation: Physical and digital collections, curation and use

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Societal Impact Statement Collections of dried plant specimens (herbaria) provide an invaluable resource for the study of many areas of scientific interest and conservation globally. Digitisation increases access to specimens and metadata, enabling efficient use across a broad spectrum of research.
Alan James Paton   +39 more
wiley   +1 more source

Mycoviruses confer hypovirulence but enhance antifungal volatile organic compound production in a phytopathogenic fungus. [PDF]

open access: yesProc Natl Acad Sci U S A
Liu Z   +17 more
europepmc   +1 more source

Range‐wide sampling reveals cryptic lineages but largely conserved mycorrhizal associations in the Japanese fairy lantern Thismia kobensis

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
The jewel‐like flowers of Thismia are as rare as they are beautiful, often recorded from only a single site per species. Access to 15 populations of T. kobensis has enabled an uncommon, range‐wide assessment of morphology, genetics, and fungal partners. Our analyses showed that T.
Kenji Suetsugu   +4 more
wiley   +1 more source

Relative Humidity Influences Aureobasidium pullulans Degradation of Polyester Polyurethane Foam. [PDF]

open access: yesEnviron Microbiol Rep
Stickney A   +8 more
europepmc   +1 more source

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