Results 21 to 30 of about 1,374,086 (326)

Revisiting a ‘simple’ fungal metabolic pathway reveals redundancy, complexity and diversity

Microbial Biotechnology, 2021
Summary Next to d‐glucose, the pentoses l‐arabinose and d‐xylose are the main monosaccharide components of plant cell wall polysaccharides and are therefore of major importance in biotechnological applications that use plant biomass as a substrate ...
Tania Chroumpi, Mao Peng, Maria Victoria Aguilar‐Pontes, Astrid Müller, Mei Wang, Juying Yan, Anna Lipzen, Vivian Ng, Igor V. Grigoriev, Miia R. Mäkelä, Ronald P. deVries   +10 more
doaj   +1 more source

Multiplex Base-Editing Enables Combinatorial Epigenetic Regulation for Genome Mining of Fungal Natural Products.

Journal of the American Chemical Society, 2022
Genome mining of cryptic natural products (NPs) remains challenging, especially in filamentous fungi, owing to their complex genetic regulation. Increasing evidence indicates that several epigenetic modifications often act cooperatively to control fungal
Fanglong Zhao, Chunxiao Sun, Zhiwen Liu, Alan Cabrera, Mario Escobar, Shunyu Huang, Qichen Yuan, Qiuyue Nie, Kevin Lee Luo, Angela S. P. Lin, Jeffrey A Vanegas, T. Zhu, Isaac B. Hilton, Xue Gao   +13 more
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GalR, GalX and AraR co‐regulate d‐galactose and l‐arabinose utilization in Aspergillus nidulans

Microbial Biotechnology, 2022
Summary Filamentous fungi produce a wide variety of enzymes in order to efficiently degrade plant cell wall polysaccharides. The production of these enzymes is controlled by transcriptional regulators, which also control the catabolic pathways that ...
Jiali Meng, Zoltán Németh, Mao Peng, Erzsébet Fekete, Sandra Garrigues, Anna Lipzen, Vivian Ng, Emily Savage, Yu Zhang, Igor V. Grigoriev, Miia R. Mäkelä, Levente Karaffa, Ronald P. deVries   +12 more
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Transcriptome analysis of Aspergillus niger xlnR and xkiA mutants grown on corn Stover and soybean hulls reveals a highly complex regulatory network

BMC Genomics, 2019
Background Enzymatic plant biomass degradation by fungi is a highly complex process and one of the leading challenges in developing a biobased economy. Some industrial fungi (e.g.
Claire Khosravi, Joanna E. Kowalczyk, Tania Chroumpi, Evy Battaglia, Maria-Victoria Aguilar Pontes, Mao Peng, Ad Wiebenga, Vivian Ng, Anna Lipzen, Guifen He, Diane Bauer, Igor V. Grigoriev, Ronald P. de Vries   +12 more
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Deletion of either the regulatory gene ara1 or metabolic gene xki1 in Trichoderma reesei leads to increased CAZyme gene expression on crude plant biomass

Biotechnology for Biofuels, 2019
Background Trichoderma reesei is one of the major producers of enzymes for the conversion of plant biomass to sustainable fuels and chemicals. Crude plant biomass can induce the production of CAZymes in T.
Tiziano Benocci, Maria Victoria Aguilar-Pontes, Roland Sándor Kun, Ronnie J. M. Lubbers, Kathleen Lail, Mei Wang, Anna Lipzen, Vivian Ng, Igor V. Grigoriev, Bernhard Seiboth, Paul Daly, Ronald P. de Vries   +11 more
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A comparative genomics study of 23 Aspergillus species from section Flavi

Nature Communications, 2020
Aspergillus fungi classified within the section Flavi include harmful and beneficial species. Here, Kjærbølling et al. analyse the genomes of 23 Flavi species, showing high genetic diversity and potential for synthesis of over 13,700 CAZymes and 1600 ...
Inge Kjærbølling, Tammi Vesth, Jens C. Frisvad, Jane L. Nybo, Sebastian Theobald, Sara Kildgaard, Thomas Isbrandt Petersen, Alan Kuo, Atsushi Sato, Ellen K. Lyhne, Martin E. Kogle, Ad Wiebenga, Roland S. Kun, Ronnie J. M. Lubbers, Miia R. Mäkelä, Kerrie Barry, Mansi Chovatia, Alicia Clum, Chris Daum, Sajeet Haridas, Guifen He, Kurt LaButti, Anna Lipzen, Stephen Mondo, Jasmyn Pangilinan, Robert Riley, Asaf Salamov, Blake A. Simmons, Jon K. Magnuson, Bernard Henrissat, Uffe H. Mortensen, Thomas O. Larsen, Ronald P. de Vries, Igor V. Grigoriev, Masayuki Machida, Scott E. Baker, Mikael R. Andersen   +36 more
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Genome-Wide Study of Conidiation-Related Genes in the Aphid-Obligate Fungal Pathogen Conidiobolus obscurus (Entomophthoromycotina)

Journal of Fungi, 2022
Fungi in the Entomophthorales order can cause insect disease and epizootics in nature, contributing to biological pest control in agriculture and forestry.
Lvhao Zhang, Tian Yang, Wangyin Yu, Xiaojun Wang, Xiang Zhou, Xudong Zhou   +5 more
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Cinnamic Acid and Sorbic acid Conversion Are Mediated by the Same Transcriptional Regulator in Aspergillus niger

Frontiers in Bioengineering and Biotechnology, 2019
Cinnamic acid is an aromatic compound commonly found in plants and functions as a central intermediate in lignin synthesis. Filamentous fungi are able to degrade cinnamic acid through multiple metabolic pathways.
Ronnie J. M. Lubbers, Adiphol Dilokpimol, Jorge Navarro, Mao Peng, Mei Wang, Anna Lipzen, Vivian Ng, Igor V. Grigoriev, Jaap Visser, Kristiina S. Hildén, Ronald P. de Vries   +10 more
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Enemy or ally: a genomic approach to elucidate the lifestyle of Phyllosticta citrichinaensis

G3: Genes, Genomes, Genetics, 2022
Members of the fungal genus PhyllostictaCitrusCitrus sinensisCitrus limonCitrus maximaPhyllostictaPhyllostictaPhyllosticta citrichinaensisPhyllostictaCitrusPhyllosticta citrichinaensisPhyllosticta ...
Valerie A Buijs, Johannes Z Groenewald, Sajeet Haridas, Kurt M LaButti, Anna Lipzen, Francis M Martin, Kerrie Barry, Igor V Grigoriev, Pedro W Crous, Michael F Seidl   +9 more
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antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

Nucleic Acids Res., 2011
Bacterial and fungal secondary metabolism is a rich source of novel bioactive compounds with potential pharmaceutical applications as antibiotics, anti-tumor drugs or cholesterol-lowering drugs.
M. Medema, K. Blin, Peter Cimermancic, V. D. Jager, Piotr Zakrzewski, M. Fischbach, T. Weber, E. Takano, R. Breitling   +8 more
semanticscholar   +1 more source