Results 41 to 50 of about 1,374,086 (326)
Carbon catabolite repression enables fungi to utilize the most favourable carbon source in the environment, and is mediated by a key regulator, CreA, in most fungi.
Mao Peng+16 more
doaj
TheiaEuk: a species-agnostic bioinformatics workflow for fungal genomic characterization
IntroductionThe clinical incidence of antimicrobial-resistant fungal infections has dramatically increased in recent years. Certain fungal pathogens colonize various body cavities, leading to life-threatening bloodstream infections.
Frank J. Ambrosio+18 more
doaj +1 more source
Panning for gold in mould: can we increase the odds for fungal genome mining?
Fungi are a rich source of bioactive small molecules. However, the large number of biosynthetic gene clusters (BGCs) encoding these molecules in their genomes suggests their biosynthetic potential is far greater than we previously appreciated. The mining
C. Gilchrist, Hang Li, Y. Chooi
semanticscholar +1 more source
A population-level invasion by transposable elements triggers genome expansion in a fungal pathogen
Genome evolution is driven by the activity of transposable elements (TEs). The spread of TEs can have deleterious effects including the destabilization of genome integrity and expansions.
Ursula Oggenfuss+10 more
semanticscholar +1 more source
Fungal Genomic Annotation [PDF]
Sequencing technology in the last decade has advanced at an incredible pace. Currently there are hundreds of microbial genomes available with more still to come. Automated genome annotation aims to analyze this amount of sequence data in a high-throughput fashion and help researches to understand the biology of these organisms.
Igor V. Grigoriev+2 more
openaire +2 more sources
Impact of genomics on fungal biology [PDF]
Fungi represent an extremely diverse and complex class of organisms, and their categorization as lower eukaryotes should by no means be mistaken as meaning low-end. At present, fungi serve as model systems for various aspects of molecular and cellular biology, for example cell cycle regulation, intracellular signaling, metabolic pathway analysis and ...
Voegele, Ralf T., Mendgen, Kurt
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Genomic and Genetic Insights Into a Cosmopolitan Fungus, Paecilomyces variotii (Eurotiales)
Species in the genus Paecilomyces, a member of the fungal order Eurotiales, are ubiquitous in nature and impact a variety of human endeavors. Here, the biology of one common species, Paecilomyces variotii, was explored using genomics and functional ...
Andrew S. Urquhart+13 more
doaj +1 more source
Comparative Genomics Platform and Phylogenetic Analysis of Fungal Laccases and Multi-Copper Oxidases
Laccases (EC 1.10.3.2), a group of multi-copper oxidases (MCOs), play multiple biological functions and widely exist in many species. Fungal laccases have been extensively studied for their industrial applications, however, there was no database ...
Jiayao Wu+3 more
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RELATe enables genome-scale engineering in fungal genomics [PDF]
Genomic DNA can be converted into sgRNA libraries for genome-wide screening of fungal factors in blood-brain barrier penetration.
Zhongming Li, Kwang Sik Kim
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