Background The genus Induratia is based on Induratia apiospora, a xylarialean pyrenomycete from New Zealand with clypeate uniperitheciate stromata, hyaline apiospores and a nodulisporium-like anamorph.
Marjorie Cedeño-Sanchez+5 more
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APX001 Is Effective in the Treatment of Murine Invasive Pulmonary Aspergillosis. [PDF]
Invasive pulmonary aspergillosis (IPA) due to Aspergillus fumigatus is a serious fungal infection in the immunosuppressed patient population. Despite the introduction of new antifungal agents, mortality rates remain high, and new treatments are needed ...
Alkhazraji, Sondus+7 more
core
Novel insights into host-fungal pathogen interactions derived from live-cell imaging [PDF]
Acknowledgments The authors acknowledge funding from the Wellcome Trust (080088, 086827, 075470 and 099215) including a Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology 097377 and FP7-2007–2013 grant agreement HEALTH-F2-2010 ...
A Casadevall+77 more
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The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou+11 more
wiley +1 more source
Biological Control of the Chagas Disease Vector Triatoma infestans with the Entomopathogenic Fungus Beauveria bassiana Combined with an Aggregation Cue: Field, Laboratory and Mathematical Modeling Assessment [PDF]
Background: Current Chagas disease vector control strategies, based on chemical insecticide spraying, are growingly threatened by the emergence of pyrethroid-resistant Triatoma infestans populations in the Gran Chaco region of South America. Methodology
Cardozo, Rubén Marino+8 more
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FfRlpA2, a conserved Fusarium effector, functions as a protease inhibitor by hijacking the E3 ubiquitin ligase IbCHYR1 to degrade the resistance factor IbZnFR, thereby promoting Fusarium pathogenicity. Conversely, the high dosage Pro::IbZnFRHap2 allele was associated with resistance to root rot disease.
Huan Zhang+14 more
wiley +1 more source
Epizootiology of the Fungal Pathogen, \u3ci\u3eZoophthora Phytonomi\u3c/i\u3e (Zygomycetes: Entomophthorales) in Field Populations of Alfalfa Weevil (Coleoptera: Curculionidae) Larvae in Illinois [PDF]
The influence of the fungal pathogen, Zoophthora phytonomi, on larvae of the alfalfa weevil, Hypera postica, was studied in three alfalfa fields in Illinois. Disease epizootics occurred in all three fields and disease onset was ob- served within a fairly
Armbrust, Edward J+3 more
core +2 more sources
Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu+13 more
wiley +1 more source
This study develops an a red/far‐red light‐controlled iPSC‐based vaccines (RIVA) based on the chimeric photosensory protein FnBphP and its interaction partner LDB3 for cancer immunotherapy. The RIVA preserves the multiple intrinsic tumor antigens of iPSCs and enables optogenetic control of the expression of the immune adjuvant type I interferon β under
Longliang Qiao+17 more
wiley +1 more source
The Hap Complex in Yeasts: Structure, Assembly Mode, and Gene Regulation
The CCAAT box-harboring proteins represent a family of heterotrimeric transcription factors which is highly conserved in eukaryotes. In fungi, one of the particularly important homologs of this family is the Hap complex that separates the DNA-binding ...
Yinhe Mao, Yinhe Mao, Changbin Chen
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