Results 231 to 240 of about 3,817,565 (379)

Novel Synthesis of the Antifungal Cyclic Lipopeptide Iturin A and Its Fluorinated Analog for Structure‐Activity Relationship Studies

open access: yesChemistry – A European Journal, EarlyView.
Iturin A is an antifungal lipopeptide with a wide range of applications. In this study, we present a novel synthesis of iturin A via enantiomeric synthesis of the β‐amino fatty acid and on‐resin cyclization. We also obtained the (S)‐epimer of iturin A, showing a dramatic loss of bioactivity, and a monofluorinated analog, which retained the bioactivity ...
Periklis Karamanis   +6 more
wiley   +1 more source

Dynamic Combinatorial Chemistry Generates Adaptative Libraries of Glyco‐Dyn[n]Arenes That can Be Templated to Produce Anti‐Adhesive Glycoconjugates Targeting Pseudomonas aeruginosa

open access: yesChemistry – A European Journal, EarlyView.
DCC enables the formation of glycocluster libraries through reversible disulfide exchange. Nanomolar ligands for multiple lectins (ConA, LecA, and LecB) were identified in a simple experimental set up, purified, and displayed nanomolar affinity with anti‐infectious properties.
Fanny Demontrond   +13 more
wiley   +1 more source

Author Correction: Functional analysis of the Aspergillus fumigatus kinome identifies a druggable DYRK kinase that regulates septal plugging

open access: yesNature Communications
Norman van Rhijn   +20 more
doaj   +1 more source

Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function

open access: yesCytoskeleton, EarlyView.
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves   +3 more
wiley   +1 more source

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