Results 101 to 110 of about 400,986 (351)
Novel Antifungal Scaffold Targeting Tubulin Overcomes Sclerotinia Sclerotiorum Resistance
Addressing pesticide resistance, novel chromone‐acylhydrazone hybrids targeting fungal tubulin are synthesized. Compound G24 potently inhibited S. sclerotiorum (EC50 = 0.21µg mL−1) and demonstrated enhanced field performance via microencapsulation, offering a sustainable strategy against resistance and for global food security.
Lihui Shao +5 more
wiley +1 more source
Culture-positive COVID-19-associated pulmonary aspergillosis (CAPA) in Germany
Background: COVID-19-associated-pulmonary-aspergillosis (CAPA) is a severe superinfection mostly affecting critically ill COVID-19 patients. Early diagnosis and clinical management of CAPA remain major clinical challenges.Here, we evaluated different ...
Leonie H. Aldejohann +7 more
doaj +1 more source
Cecropins contribute to Drosophila host defense against a subset of fungal and Gram-negative bacterial infection [PDF]
Alexia Carboni +4 more
openalex +1 more source
Saprolegnia diclina IIIA and S. parasitica employ different infection strategies when colonizing eggs of Atlantic salmon, Salmo salar L. [PDF]
Acknowledgements The work has been funded by the European Commission through the EU Marie Curie ITN project SAPRO (238550) (MMS, AW). We would also like to acknowledge support from the BBSRC and the University of Aberdeen (PvW) and Landcatch and AquaGen ...
Evensen, O. +6 more
core +1 more source
Tinea is a common fungal infection that can affect the skin, nails and hair. Tinea infection has a variety of clinical manifestations and affects all age groups, ranging from tinea pedis in adults to tinea capitis in pre-pubertal children.This article provides an updated overview of the common clinical manifestations and practical approaches to the ...
Tom, Kovitwanichkanont, Alvin H, Chong
openaire +3 more sources
Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar +7 more
wiley +1 more source
This study reveals that actin remodeling regulates mitochondrial elongation as a defense strategy in plants. Flagellin perception induces fusion‐dependent elongation, supported by cortical actin bundles, to repair damage and boost ATP and ROS production.
Junxiu Hou +5 more
wiley +1 more source
<h1 style="margin-right: -5.4pt; text-indent: 26.0pt;"><span style="font-weight: normal;" lang="EN-US">Yeasts and moulds now rank amongst the 10 most frequently isolated pathogens in febrile patients with an impaired immune system.
Ben E de Pauw
doaj +3 more sources
Principles for Rigorous Design and Application of Synthetic Microbial Communities
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang +21 more
wiley +1 more source
Progressive disseminated histoplasmosis, caused by H. capsulatum, is a life-threatening illness and is an AIDS-defining opportunistic infection. It is neglected, worryingly under-diagnosed, and often misdiagnosed as cancer or tuberculosis with fatal ...
Felix Bongomin +2 more
doaj +1 more source

