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Fungal Keratitis: Diagnosis, Management, and Recent Advances [PDF]

Clinical Ophthalmology
Ramy Awad,1 Alaa Atef Ghaith,2 Khaled Awad,1 Marina Mamdouh Saad,1 Ahmed Ak Elmassry2 1Department of Ophthalmology, Alexandria General Ophthalmology Hospital, Alexandria, Egypt; 2Department of Ophthalmology, Faculty of Medicine, Alexandria University ...
Awad R, Ghaith AA, Awad K, Mamdouh Saad M, Elmassry AA   +4 more
doaj   +3 more sources

Development of nanodrug-based eye drops with good penetration properties and ROS responsiveness for controllable release to treat fungal keratitis

NPG Asia Materials, 2023
Fungal keratitis is challenging to diagnose and treat and remains a significant cause of blindness worldwide. The easiest and most common method of drug delivery for patients with fungal keratitis is eye drop administration.
Panhong Niu, Yuelan Wu, Fanxing Zeng, Shuping Zhang, Sijin Liu, Hua Gao   +5 more
doaj   +2 more sources

Recent Perspectives in the Management of Fungal Keratitis [PDF]

Journal of Fungi, 2021
Mycotic keratitis is common in warm, humid regions with a varying profile of pathogenic fungi according to geographical origin, socioeconomic status, and climatic condition. Clinical diagnosis can be challenging in difficult cases and those refractory to treatment.
Nimmy Raj, Murugesan Vanathi, Nishat Hussain Ahmed, Noopur Gupta, Neiwete Lomi, Radhika Tandon   +5 more
openaire   +5 more sources

Immunologic mechanism of fungal keratitis

International Journal of Ophthalmology, 2021
Fungal keratitis (FK) is a refractory disease that poses a serious threat to vision, with common risk factors like eye trauma, contact lens wearing, topical corticosteroids and antibiotic abuse. Nowadays, topical and systemic anti-fungal drugs and ocular surgeries are still the main therapeutic modalities.
Ruibo Yang, Chen Zhang, Hui Liu, Xiaoxiao Lu, Li-Ping Wu, Yue Huang, Shaozhen Zhao, Zhe Jia, Yichen Gao   +8 more
openaire   +5 more sources

Medical interventions for fungal keratitis. [PDF]

Cochrane Database of Systematic Reviews, 2015
BACKGROUND: Fungal keratitis is a fungal infection of the cornea. It is common in lower income countries, particularly in agricultural areas but relatively uncommon in higher income countries. Although there are medications available, their effectiveness
Evans, Jennifer R, FlorCruz, Nilo Vincent   +1 more
core   +5 more sources

Fungal Keratitis, Epidemiology and Outcomes in a Tropical Australian Setting [PDF]

Tropical Medicine and Infectious Disease
Background: Fungal keratitis is an ophthalmic emergency that can cause visual impairment and blindness. We reviewed the epidemiology and clinical features of fungal keratitis in a tropical Australian setting.
Leah N. Kim, Hema Karthik, Kate Elizabeth Proudmore, Sarah Elizabeth Kidd, Robert William Baird   +4 more
doaj   +2 more sources

Medical interventions for fungal keratitis [PDF]

, 2003
Fungal keratitis is common in agricultural tropical countries but relatively uncommon in developed countries. Although there are medications available, their effectiveness is unclear.The purpose of the review was to examine the effect of different antifungal drugs in the management of fungal keratitis.We searched the Cochrane Central Register of ...
NV FlorCruz, Ildefonso V Peczon
openalex   +4 more sources

The role of PPAR in fungal keratitis. [PDF]

Front Immunol
The treatment of fungal keratitis(FK) remains challenging due to delayed fungal detection and the limited effectiveness of antifungal drugs. Fungal infection can activate both innate and adaptive immune responses in the cornea. Fungi stimulate the production of oxidative stress-related biomarkers and mediate the infiltration of neutrophils, macrophages,
Zhou H, Zhang H, Bi M, Zhang W.
europepmc   +4 more sources

The role of fungi in fungal keratitis [PDF]

Experimental Eye Research, 2021
Fungal keratitis (FK) accounts for approximately half of the microbial keratitis encountered in low middle income countries (LMICs) and predominantly affect the working rural-poor. FK causes significant morbidity with the majority of patients left with moderate or worse visual impairment and approximately 25% requiring expensive and often unsuccessful ...
Bethany Mills, Naveen Radhakrishnan, Siva Ganesa Karthikeyan Rajapandian, Gunasekaran Rameshkumar, Prajna Lalitha, N. Venkatesh Prajna   +5 more
openaire   +3 more sources

First‐Line Osimertinib in Patients with EGFR‐Mutant Advanced Non‐Small Cell Lung Cancer: Outcome and Safety in the Real World: FLOWER Study

The Oncologist, EarlyView., 2021
Abstract Lessons Learned Osimertinib has confirmed effectiveness in this real‐world population of patients with EGFR‐mutant advanced non‐small cell lung cancer. Thromboembolic events occur more frequently than previously reported, suggesting a thrombotic diathesis that requires further investigation. Patients with at least three metastatic sites, brain
Martina Lorenzi, Alessandra Ferro, Fabiana Cecere, Daniela Scattolin, Alessandro Del Conte, Alessandro Follador, Sara Pilotto, Valentina Polo, Mariacarmela Santarpia, Rita Chiari, Alberto Pavan, Alessandro Dal Maso, Valentina Da Ros, Giada Targato, Sabrina Vari, Stefano Indraccolo, Fiorella Calabrese, Stefano Frega, Laura Bonanno, Pier Franco Conte, Valentina Guarneri, Giulia Pasello   +21 more
wiley   +1 more source