Advanced Science, EarlyView.L14‐8, a small molecule derived from the marketed drug ezetimibe, potently inhibits advanced prostate cancer independent of androgen receptor signaling. L14‐8 binds PLK1, triggering its ubiquitin‐mediated degradation. This activates TP53‐dependent transcription of SAT1, inducing ferroptosis and suppressing tumor growth in prostate cancer patient ...
Yu Zhang +8 more
wiley +1 more source
An Atomically Dispersed Photocatalyst for Undirected para‐Selective C─H Bond Functionalizations
Angewandte Chemie, EarlyView.This study presents an atomically dispersed recyclable heterogeneous photocatalytic method for para‐selective trifluoromethylation of electron‐deficient arenes without directing groups. Unlike previous substrate‐dependent approaches, this recyclable, atomically dispersed photocatalyst enables scalable synthesis of bioactive trifluoromethylated ...
Suman Pradhan +16 more
wiley +2 more sources
Rice apoplastic CBM1-interacting protein counters blast pathogen invasion by binding conserved carbohydrate binding module 1 motif of fungal proteins. [PDF]
PLoS Pathog, 2022 Takeda T +12 more
europepmc +1 more source
Protein Synthesis During Fungal Spore Germination II. Aminoacyl-soluble Ribonucleic Acid Synthetase Activities During Germination of Botryodiplodia theobromae Spores [PDF]
, 1968 James L. Van Etten, Robert Brambl
openalex +1 more source
Microbiology and Molecular Biology Reviews, 2018 SUMMARY Filamentous fungi constitute a large group of eukaryotic microorganisms that grow by forming simple tube-like hyphae that are capable of differentiating into more-complex morphological structures and distinct cell types.
M. Riquelme +12 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study illustrates the impact of viruses on carbon cycling in soils with different availabilities of carbon. In conditions of low carbon availability, viruses adopt a lysogenic lifestyle, integrate into the host genomes and facilitate the degradation of carbon.
Mingfeng Liu +8 more
wiley +1 more source
iScience, 2021 Summary: Phagocytosis and autophagy play critical roles in immune defense. The human fungal pathogen Cryptococcus neoformans (Cn) subverts host autophagy-initiation complex (AIC)-related proteins, to promote its phagocytosis and intracellular parasitism ...
Shengli Ding +14 more
doaj
Drought Exposed Burkholderia seminalis JRBHU6 Exhibits Antimicrobial Potential Through Pyrazine-1,4-Dione Derivatives Targeting Multiple Bacterial and Fungal Proteins. [PDF]
Front Microbiol, 2021 Prasad JK +3 more
europepmc +1 more source
Protein Synthesis During Fungal Spore Germination: Differential Protein Synthesis During Germination of Botryodiplodia theobromae Spores [PDF]
, 1972 James L. Van Etten +2 more
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Production of therapeutic proteins in fungal hosts [PDF]
Expert Opinion on Biological Therapy, 2004 Tillman U. Gerngross, Nicole Ballew
openaire +3 more sources