Results 161 to 170 of about 7,287,208 (286)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Stroke-CORE: master study protocol of the national cohort of the specialty network stroke within the network university medicine in Germany. [PDF]

Neurol Res Pract
Wiegand FN, Alonso A, Audebert HJ, Barlinn J, Bendszus M, Brinkmann F, Cheng B, Dzietko M, Feil K, Flöel A, Franzisket C, Gerstl L, Grefkes C, Günther K, Harringa K, Jiru-Hillmann S, Kanwisch JL, Kerti L, Köhrmann M, Kopczak A, Kunze C, Linn J, Mengel A, Michalski D, Minnerup J, Nolte CH, Otte C, Purrucker J, Saur D, Schäbitz W, Schwab S, Szabo K, Uphaus T, Wachter R, Wagner M, Heuschmann PU, Gertz K, Thomalla G.   +37 more
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

fur n / fur mark

fur nThe fur mark 'E.B' was known throughout the Fur Trade as being the finest. E.B represents Eskimo Bay.PRINTED ITEM DNE SupOCT 7 1988 WKG. M.

core  

Fur pillbox

, 1950
Pillbox of off-white fur felt with brim of white (rabbit?) fur. Unlined; white grosgrain ribbon headband.
Velda Original
core  

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Fabureau Fur Trading Contract

One of the earliest manuscripts in the library, this contract calls for trader Charles Fabereau to deliver supplies to Sieur Dumont, a French officer commanding the Miamis post (now Fort Wayne), and return to Montreal with Dumont's fur pelts to sell at a
Charles Fabereau and Sieur Dumont
core  

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source