Results 161 to 170 of about 40,816 (213)

GLP‐1 agonists and the gut microbiome: A bidirectional relationship

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists have transformed the management of type 2 diabetes mellitus (T2DM) and obesity, yet their interactions with the gut microbiome remain an emerging frontier in pharmacological and metabolic research.
Srinivas Kamath   +2 more
wiley   +1 more source

Contrasting roles of school and public libraries in lower primary pupils' reading

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Libraries represent an important institutional component of children's reading socialisation, yet their role is often treated as uniform despite substantial differences between school and public libraries. This study examines how visits to school and public libraries relate to pupils' reading attitudes, practices and self‐assessed reading ...
Kateřina Balcarová, Jiří Balcar
wiley   +1 more source

Research on synthesis of microwave‐assisted heterocyclic compounds with eco‐friendly solvents and transition metals via C–H activation

open access: yesBulletin of the Korean Chemical Society, EarlyView.
This review summarizes microwave‐assisted transition‐metal catalysis for constructing N‐ and O‐heterocycles, highlighting rapid C–H and pre‐activated C–X activation, improved selectivity, and green synthetic efficiency. Abstract Microwave‐assisted organic synthesis provides a rapid and sustainable platform for synthesizing various heterocycles ...
Woo‐Jin Park, Ye Ri Han, Hyejeong Lee
wiley   +1 more source

Trithio‐naphthalic anhydride‐based photosensitizer for photodynamic activity

open access: yesBulletin of the Korean Chemical Society, EarlyView.
A trithio‐naphthalic anhydride photosensitizer (NapS) is created by simple thionation, switching excited‐state pathways to deliver both type I and type II reactive oxygen species. NapS enables efficient photodynamic therapy under normoxia and hypoxia, achieving strong cancer cell killing with low dark toxicity.
Thanh Chung Pham   +6 more
wiley   +1 more source

An automated microfluidic biosensor with bispecific rabbit monoclonal antibody and nanozyme‐bioenzyme composite for dual antibiotic detection

open access: yesBMEMat, EarlyView.
This study introduces an automated microfluidic biosensor for simultaneous detection of florfenicol and thiamphenicol in environmental water. By integrating a phage‐screened bispecific rabbit monoclonal antibody with a nanozyme‐bioenzyme composite, the system achieves sensitive dual‐antibiotic detection. Coupled with smartphone‐based sensing, it offers
Fuyuan Zhang   +11 more
wiley   +1 more source

Early evolutionary history of the seed

open access: yesBiological Reviews, EarlyView.
ABSTRACT The seed is an essential stage in the life history of gymnospermous and angiospermous plants, facilitating both their survival and dispersal. We reappraise knowledge of the evolutionary history of the gymnospermous seed, from its origin in the late Devonian through to the well‐known end‐Permian extinctions – an interval encompassing the ...
Richard M. Bateman   +2 more
wiley   +1 more source

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