Results 121 to 130 of about 302 (208)

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Elucidating the physiological significance of iodate reduction in Shewanella species

mLife, EarlyView.
Abstract The reduction of iodate by Shewanella species plays a crucial role in iodine biogeochemical cycling. However, the physiological significance of this reduction process remains poorly understood, because Shewanella species are capable of reducing only low concentrations of iodate.
Ziyi Wang, Lingyu Hou, Yidan Hu, Zhou Jiang, Yiran Dong, Liang Shi, Yongguang Jiang   +6 more
wiley   +1 more source

AGRN‐, LRP4‐, MUSK‐Related CMS: Clinical, Neurophysiological, Morphological, Genetic and Pathological Mechanisms

Muscle &Nerve, EarlyView.
ABSTRACT Congenital myasthenic syndromes (CMS) are inherited disorders caused by mutations in genes encoding proteins essential for neuromuscular junction (NMJ) function. Pathogenic variants have been identified in more than 35 genes, underscoring the complexity of synaptic biology and the wide range of mechanisms that can compromise neuromuscular ...
Rocio‐Nur Villar‐Quiles, Damien Sternberg, Marie‐Christine Nougues, Arnaud Isapof, Bruno Eymard, Stéphanie Bauché   +5 more
wiley   +1 more source

Crisis Preparation, Capacity Building, and Community Resilience: Lessons From Maui

Nonprofit Management and Leadership, EarlyView.
ABSTRACT The 2023 Maui wildfires provide a unique context to explore the impact of nonprofit crisis networks taking a proactive role in community crisis response, leveraging resources, expertise, and networks. The Hawaiʻi Community Foundation (HCF) has been a key player in Maui's local response, providing critical support, mobilizing volunteers, and ...
Lauren Azevedo, Kaila Witkowski, Ratna Dougherty, Christa Remington   +3 more
wiley   +1 more source

Interplanetary frontiers: terraforming from an invasion science perspective

Oikos, EarlyView.
The pursuit of a multi‐planetary existence represents one of humanity's greatest frontiers. If applied justly, it offers an opportunity to extend its civilization's lifespan amid escalating sustainability crises on Earth. One approach increasingly gaining traction is terraforming, a hitherto theoretical ecological and evolutionary experiment revolving ...
Teun Everts, Ronaldo Sousa, Phillip J. Haubrock   +2 more
wiley   +1 more source

Sources of Strength for School‐Based Suicide Prevention: Key Implementation Strategies Based on School Professional Perspectives

Psychology in the Schools, EarlyView.
ABSTRACT As concerns for rising rates of youth suicide and suicidal thoughts and behaviors continue to grow, there is a need to prioritize school‐based suicide prevention programs. Despite evidence documenting the effectiveness of school‐based prevention programs for reducing suicide‐related risk in adolescents, schools face numerous barriers to ...
Marisa E. Marraccini, Maya Gutman, Layne A. Wetherbee, Jessica R. Jacobs, Donald Christian Fisher, Dorothy L. Espelage, Sarah Haley McGlothin, Denise Yookong Williams, Paul Lanier   +8 more
wiley   +1 more source

Deformation, Creep, and Dynamics in Glassy Ionomers

Journal of Polymer Science, EarlyView.
Ionic architecture tunes the inelastic deformation of glassy ionomers. Simulations show that ionic associations leave the small‐strain elastic baseline nearly unchanged, but strongly reinforce yielding, strain hardening, and creep resistance. Polyampholyte architectures suppress nonaffine mobility and stress‐induced fluidization most effectively by ...
Nazanin Sadeghi, Fardin Khabaz
wiley   +1 more source

Beyond forests: Harnessing conservation gardening for open biomes in Brazil

PLANTS, PEOPLE, PLANET, EarlyView.
Urban gardening offers an innovative conservation strategy by integrating native ornamental species into urban landscapes. We evaluated the ornamental potential of the Brazilian flora by comparing the representation of species from forests versus open biomes (focusing on campo rupestre grasslands) and introduced and validated the Index of Ornamental ...
Flávia Santos Faria, Luciane Vilela Resende, Fernando A. O. Silveira   +2 more
wiley   +1 more source

Pro‐197 mutations confer resistance to thiencarbazone but not to foramsulfuron in ALS‐resistant Poa annua populations

Pest Management Science, EarlyView.
Foramsulfuron remains effective on Pro‐197 Poa annua, but co‐formulation with thiencarbazone reduces efficacy due to limited activity and antagonism. Therefore, foramsulfuron + thiencarbazone should be used in fields without ALS‐resistant weeds to ensure effective in‐crop control.
Vijaya Bhaskar Alwarnaidu Vijayarajan, Iniya Vijayakumar, Rafa Ruiz‐Partida, Fabian Runge, Joel Torra, Jorge Lozano‐Juste, Patrick Dermot Forristal   +6 more
wiley   +1 more source

Mortality in an invasive ant does not scale linearly with fipronil exposure

Pest Management Science, EarlyView.
Increasing fipronil concentration did not linearly increase yellow crazy ant mortality when introduced via horizontal transfer; high doses may limit food sharing. Queen mortality was low, and surviving workers were averse to feeding. Abstract Background Controlling eusocial invasive and other pestiferous insects is difficult.
Peter Yeeles, Angela Strain, Lori Lach
wiley   +1 more source