Results 131 to 140 of about 3,758,420 (297)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

A COLLECTION FOR ENRICHING THE SOCIAL STUDIES CLASSROOM: INSTRUCTIONAL TECHNIQUES IN GEOGRAPHY EDUCATION

open access: yesSakarya Üniversitesi Eğitim Fakültesi Dergisi, 2013
Having explained clearly in researches, unfortunately, social studies education, as one of the major part of primary education, is not going further than a boring lesson for students.
Alper Kesten
doaj  

Disadvantaged learners and VET to higher education transitions [PDF]

open access: yes
This paper synthesises what is currently published on the access and participation of disadvantaged learners in higher-level vocational education and training (VET) qualifications and higher education, and their transitions from lower-level VET ...
Tabatha Griffin
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

The Motivations and Outcomes of Studying for Part-time Mature Students Completing Higher Education Programmes at Further Education Colleges [PDF]

open access: yes, 2014
Part-time students account for 31% of higher education students in the UK and 56% of part-time undergraduate students are over the age of 30 on entry (UniversityUK 2013).
Cattell, Chris, Wood, Colin
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

A história da educação programada: uma aproximação da história da educação ensinada nos cursos de pedagogia em Belo Horizonte

open access: yesRevista Brasileira de História da Educação, 2012
Following the steps of the SBHE and other researchers, this work aims at focusing on the necessity to systematically discuss the question of how the history of education is being taught in Brazil.
Luciano Mendes de Faria Filho   +1 more
doaj  

Embedding Outdoor Relational Education in Academia: Perceived Barriers and Opportunities at a Dutch University

open access: yesAustralian Journal of Environmental Education
Calls for innovating environmental and sustainability education—including higher education—have been voiced for many years. New approaches are gaining traction, including the Wild Pedagogies framework and notions of rewilding education.
Koen Arts   +3 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

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