Results 61 to 70 of about 2,669,568 (271)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Motivations and Attitudes Toward Further Education: A Cross-Sectional, Descriptive Predictive Study

Nursing Reports
Background: Educational requirements in healthcare are constantly evolving, and understanding nurses’ motivations toward continuing education is critical to designing nursing programs, developing workforce strategies, and ensuring better healthcare ...
Ivana Sušilović, Marija Ljubičić, Tatjana Matijaš, Ivana Bokan, Mario Marendić   +4 more
doaj   +1 more source

Studying learning in the healthcare setting: the potential of quantitative diary methods

Perspectives on Medical Education, 2015
Quantitative diary methods are longitudinal approaches that involve the repeated measurement of aspects of peoples’ experience of daily life. In this article, we outline the main characteristics and applications of quantitative diary methods and discuss ...
Yvette Yvette Ciere, Debbie Jaarsma, Annemieke Visser, Robbert Sanderman, Evelien Snippe, Joke Fleer   +5 more
doaj   +1 more source

Thriving in the 21st century: Learning Literacies for the Digital Age (LLiDA project): Executive Summary, Conclusions and Recommendations [PDF]

, 2009
LLiDA set out to: review the evidence of change in the contexts of learning, including the nature of work,nknowledge, social life and citizenship, communications media and other technologies review current responses to these challenges from the ...
Beetham, Helen, Littlejohn, Allison, McGill, Lou   +2 more
core  

Teaching the Emergency Department Patient Experience: Needs Assessment from the CORD-EM Task Force. [PDF]

, 2016
INTRODUCTION: Since the creation of Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) patient satisfaction (PS) scores, patient experience (PE) has become a metric that can profoundly affect the fiscal balance of hospital systems,
Druck, Jeffrey, Finefrock, Douglas, London, Kory S., Silver, Matthew   +3 more
core   +3 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

New perspectives on civic engagement as outcome of higher education: an exploratory case study

Frontline Learning Research
This study explores the potential of a new perspective on research into the impact higher education has on the civic engagement of students. We propose a shift from viewing engagement itself as the key dependent variable to two ‘fundamental constituents’
Oscar van den Wijngaard, Simon Beausaert, Wim Gijselaers, Mien Segers   +3 more
doaj   +1 more source

"Abstinence Unless Married" Education [PDF]

, 1998
States that use abstinence unless married federal funds must follow the federal restrictions in spending federal dollars. While this spending rule is not particularly controversial, federal law typically does not delineate what can and can not be taught ...

core  

Business models for MOOC platform providers in digital education using the example of xMOOCs. Stimulations for academic further education?! [PDF]

, 2017
Dieser Beitrag beleuchtet Geschäftsmodelle für xMOOCs. Zugrunde liegen Befunde einer Studie für die Plattformbetreiber Coursera, Udacity, edX und iversity.
Franken, Oliver B. T.
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source