Results 101 to 110 of about 35,689 (156)

Advancing Intervertebral Disc Biology via Omics: Implications for Nucleus Pulposus Progenitor Cell‐Based Regeneration

open access: yesJOR SPINE, Volume 8, Issue 4, December 2025.
Intervertebral disc degeneration (IDD) is a multifactorial condition underpinned by complex molecular mechanisms. This review highlights advances in RNA sequencing and multi‐omics approaches that have elucidated gene regulatory networks, cellular heterogeneity, and progenitor cell dynamics in the nucleus pulposus.
Anja Stirnimann   +3 more
wiley   +1 more source

Therapeutic Approaches for Enhancing Spinal Fusion in Low Back Pain: A Review With a Focus on the Elderly

open access: yesJOR SPINE, Volume 8, Issue 4, December 2025.
The review summarizes the current clinical problems of non‐spinal fusions in orthopaedics. I refers to selected biological examples of how ossification can be better achieved in elderly patients. ABSTRACT Background Low back pain (LBP) is a prevalent cause of disability worldwide, particularly among the elderly, with degenerative spinal conditions ...
Shuimu Chen   +5 more
wiley   +1 more source

Progression and Metastasis of Lung Cancer: Clinical Features, Molecular Mechanisms, and Clinical Managements

open access: yesMedComm, Volume 6, Issue 12, December 2025.
Lung cancer represents a significant global health threat. Despite progress in treatment, metastasis continues to present a major clinical challenge. This article reviews the metastases of lung cancer to the liver, bone, and brain, focusing on clinical symptoms, molecular mechanisms, and treatment strategies.
Yunkui Zhang   +4 more
wiley   +1 more source

Review of the tetrapod skull–neck boundary: implications for the evolution of the atlas–axis complex

open access: yesBiological Reviews, Volume 100, Issue 6, Page 2435-2470, December 2025.
ABSTRACT This review describes variation in modern and fossil occiput–atlas–axis complex anatomy of total group Tetrapoda with the aim of documenting the range of structural variation throughout their evolutionary history to establish grounds for comparison of the complex between tetrapod clades.
Dana E. Korneisel, Hillary C. Maddin
wiley   +1 more source

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