The Journal of Physiology, EarlyView.Abstract figure legend The volume‐regulated anion channel (VRAC), composed of leucine‐rich repeat‐containing 8 (LRRC8) proteins, serves both canonical and non‐canonical functions in vertebrate cells. The canonical function of this channel relates to its original description, which is homeostatic regulation of cell volume in response to hypotonic ...
Sergei Yanushkevich +9 more
wiley +1 more source
Prediction of fusion cage subsidence after transforaminal lumbar interbody fusion based on MRI endplate bone quality. [PDF]
Quant Imaging Med SurgLi C +9 more
europepmc +1 more source
Persistence of quantal synaptic vesicle recycling in virtual absence of dynamins
The Journal of Physiology, EarlyView.Abstract figure legend Figure depicts the key finding from this study. While loss of all dynamins severely debilitates synaptic vesicle retrieval following repetitive activity, retrieval and recycling of individual synaptic vesicles following spontaneous fusion or sparse stimulation are minimally affected.
Olusoji A. T. Afuwape +4 more
wiley +1 more source
Developing a Deep Learning Radiomics Model Combining Lumbar CT, Multi-Sequence MRI, and Clinical Data to Predict High-Risk Adjacent Segment Degeneration Following Lumbar Fusion: A Retrospective Multicenter Study. [PDF]
Global Spine JZou C +5 more
europepmc +1 more source
The contemporary management of prostate cancer
CA: A Cancer Journal for Clinicians, EarlyView.Abstract Prostate cancer is the most common cancer in two thirds of the world, with an expected doubling in both incidence and mortality in the next two decades. No strong environmental associations exist for the development of prostate cancer; therefore, lifestyle measures are unlikely to mitigate this increasing burden.
Deep Chakrabarti +11 more
wiley +1 more source
Cervical Pyogenic Spondylitis: A Comprehensive Review of Diagnosis and Treatment Strategy. [PDF]
J Clin MedKong CG, Kim SK, Park JB.
europepmc +1 more source
JOR SPINE, Volume 8, Issue 3, September 2025.This is the first in vivo study to demonstrate that ultrafine‐grained stainless steel possesses potential antibacterial properties capable of resisting the adhesion of bacteria and, subsequently, microcolony formation and biofilm maturation. Incorporating ultrafine‐grained materials in the manufacture of orthopedic implants or medical devices could ...
Mitsuhiro Nishizawa +5 more
wiley +1 more source
Modeling and construction of nomogram of cage subsidence after single-segment transforaminal lumbar interbody fusions. [PDF]
J Orthop Surg ResZhan J +6 more
europepmc +1 more source
American Journal of Medical Genetics Part A, Volume 197, Issue 8, August 2025.ABSTRACT NPR3‐related tall stature is characterized by tall stature, elongated big toes, and additional epiphyses in hand and foot bones. The condition is caused by biallelic loss‐of‐function variants affecting natriuretic peptide receptor 3 (NPR3). Five individuals from four different families have been reported.
Pierre Moffatt +4 more
wiley +1 more source
Forearm bone mineral density predicts subsidence of titanium mesh cage after anterior cervical corpectomy and fusion in patients with cervical spondylosis. [PDF]
J Orthop Surg ResWang J +8 more
europepmc +1 more source