Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska +4 more
wiley +1 more source
Clinical and Radiological Outcomes of Monosegmental Minimally Invasive Transforaminal Lumbar Interbody Fusion for High-Grade Spondylolisthesis: A 3-Year Observational Study. [PDF]
Liu C, Wang Y, Li C, Nie P.
europepmc +1 more source
ABSTRACT Introduction Cytokine release syndrome (CRS) is a systemic inflammatory response triggered by various factors, including infection and immunotherapy. Due to its nonspecific presentation, distinguishing CRS from other life‐threatening conditions remains challenging.
Kei Nagase +9 more
wiley +1 more source
Case Report: Diagnostic and therapeutic challenges of secondary spinal tuberculosis following percutaneous vertebroplasty: a case of staged surgery with bone cement retention report. [PDF]
Shuai Q, Tian J, Yang W, Huang S.
europepmc +1 more source
ABSTRACT Background Preclinical spine research is limited by heterogeneous experimental reporting, fragmented documentation, and barriers to reproducibility and translational alignment. Large language models (LLMs) and related artificial intelligence (AI) technologies may support semantic interpretation, structured data extraction, and reasoning over ...
Siegmund Lang +5 more
wiley +1 more source
A Novel Titanium End-Disc-Assisted Allograft Preparation System for Anterior Cervical Corpectomy and Fusion: Development and Preliminary Biomechanical Evaluation. [PDF]
Chang CC, Huang SF, Huang PC, Lin CL.
europepmc +1 more source
ABSTRACT Background The vertebral bony endplate (BEP) plays a role in regulating both mechanical load transfer and nutrient transport to the intervertebral disc, functions strongly influenced by its microstructural porosity. Variations in porosity impact bone strength, elasticity, and solute diffusion, affecting its overall mechanical competence ...
Ahmad Alminnawi +5 more
wiley +1 more source
ABSTRACTBackgroundLow back pain remains the leading cause of disability worldwide, with intervertebral disc degeneration representing a major biological contributor. Although cell‐based therapies have shown promise in preclinical models, clinical translation has yielded modest and inconsistent outcomes.
Tynhinane Hamidouche +9 more
wiley +1 more source
Feasibility and clinical efficacy of minimally invasive techniques in the treatment of type Ⅱ/Ⅲ brucellar spondylitis. [PDF]
Yang X +5 more
europepmc +1 more source
Biomaterials for vertebral body repair: interior augmentation and total replacement-a literature review of bone fusion outcomes in clinical studies. [PDF]
Moura DL +6 more
europepmc +1 more source

