Results 221 to 230 of about 52,520 (266)

Expanding the Evaluation of Skeletal Anomalies in Patients With KBG Syndrome: Recommendations for Clinical Practice

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1306-1314, June 2026.
ABSTRACT KBG syndrome is a rare autosomal dominant neurodevelopmental disorder caused by ANKRD11 haploinsufficiency and is characterized by short stature, distinctive facial features, intellectual disability or developmental delay, congenital anomalies and skeletal anomalies.
Marit van der Leij   +5 more
wiley   +1 more source

A Network‐Based Approach to Understanding Key Signaling Pathways in Intervertebral Disc Biology

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
A literature‐based signaling network capturing the most relevant pathways in human nucleus pulposus cells was first constructed from curated biological evidence. The network was then translated into a system of ordinary differential equations to derive steady‐state solutions and define median baseline activity levels.
Sofia Tseranidou   +11 more
wiley   +1 more source

Fracturas por estallido toracolumbares: pasado, presente y futuro. [PDF]

open access: yes, 2006
Escribá Roca, Ismael   +2 more
core  

Deletion of a Pax1 Sex‐Associated Genomic Region Associated With Adolescent Idiopathic Scoliosis Leads to Disc Degeneration, Instability, and Vertebral Rotation in Mice

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
Overview of the effects of Pax1‐SAR deletion on gene expression, IVD degeneration, and resultant scoliotic‐like curvature between sexes. Proposed mechanism of sex‐dependent changes in gene expression in females (right) and males (left), resulting in sex‐dependent disc degeneration and scoliotic phenotypes.
Edward C. Moody   +4 more
wiley   +1 more source

Platelet‐Rich Fibrin Induces New Bone Formation to Promote Extreme Lateral Interbody Fusion of Spine in Rabbits

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
Preparation process of PRF and its promotion of intervertebral fusion. The rabbit lateral fusion model proves that PRF can promote the intervertebral fusion rate of allograft bone. In vitro experiments can be observed that PRF promotes the osteogenic expression of BMSCS.
Weijian Wang   +5 more
wiley   +1 more source

Larger Lumbar Vertebral Body Osteophyte Volume Is Associated With Older Age and a More Caudal Vertebral Level in Individuals With Chronic Low Back Pain

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
Procrustes analysis was used to match osteophyte‐free lumbar vertebral bodies to lumbar vertebral bodies containing osteophytes. The volume of the reference library bone was subtracted to create an osteophyte model, from which regional osteophyte volumes were calculated.
Clarissa LeVasseur   +8 more
wiley   +1 more source

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