Results 151 to 160 of about 1,777,078 (318)
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
A brief history of the magnetic fusion program from the point of view of a stellarator enthusiast who worked at a major tokamak laboratory.
"Johnson, L. John"
core
Comparison of tracklet fusion and distributed Kalman filter for track fusion
8 S.In track fusion, the measurements of individual sensors for each target are processed to generate local state estimates, which are then fused to obtain the global state estimate for the target. When there is no process noise or the fusion rate equals
Chong, C.-Y. +3 more
core
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Review of the mathematical foundations of data fusion techniques in surface metrology
The recent proliferation of engineered surfaces, including freeform and structured surfaces, is challenging current metrology techniques. Measurement using multiple sensors has been proposed to achieve enhanced benefits, mainly in terms of spatial ...
Wang, Jian +4 more
core +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Multi Level Fusion of Competitive Sensors for Automotive Environment Perception
A reference sensor system, consisting of a multilayer laser scanner and a stereo camera system, is used for detecting vehicle surroundings. Via a novel multi level multi sensor fusion framework the heterogeneous sensor information can be fused on three ...
Kozempel, Karsten, Haberjahn, Mathias
core
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
An Overview of Classifier Fusion Methods
A number of classifier fusion methods have been recently developed opening an alternative approach leading to a potential improvement in the classification performance.
Ruta, Dymitr, Gabrys, Bogdan
core

