Autophagosome marker, LC3, is released extracellularly via several distinct pathways
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Cross-dataset late fusion of Camera-LiDAR and radar models for object detection. [PDF]
Ali A, Tawfik MM, Saafan MM.
europepmc +1 more source
Deep learning based cloud detection for remote sensing images by the fusion of multi-scale convolutional features. [PDF]
Zhiwei Li +5 more
openalex
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Development of a split-toxin CRISPR screening platform to systematically identify regulators of human myoblast fusion. [PDF]
Zhang H +13 more
europepmc +1 more source
Synergy in Neuroimaging: PET-CT and MRI Fusion for Enhanced Characterization of Brain Pathology [PDF]
Nivedita Radder +3 more
openalex +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions. [PDF]
Jiang S +7 more
europepmc +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source

