Results 221 to 230 of about 3,882,403 (320)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

The CARM beam-wave interaction and cavity design

EPJ Web of Conferences, 2017
Di Palma E., Dattoli G., Ceccuzzi S., Sabia E., Ravera G. L., Spassovsky I., Mirizzi F., Doria A., Tuccillo A.A., Gallerano G.P.   +9 more
doaj   +1 more source

Actomyosin contractility and a threshold of cadherin cell adhesion are required during tissue fusion. [PDF]

J Cell Biol
Teng CS, Curtis SW, Brewer GC, Leslie-Clarkson EJ, Bush JO.   +4 more
europepmc   +1 more source

Off-Site Geological Surveying of Longwall Face Based on the Fusion of Multi-Source Monitoring Data [PDF]

Mengbo Zhu, Ruoyu Rong, Zhizhen Liu, Xuebin Qin, Haonan Zhang, Suk‐Jo Kang   +5 more
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Comprehensive Molecular Diagnostic Tests in Non-Small Cell Lung Cancer: Frequency of <i>ALK</i>, <i>ROS1</i>, <i>RET</i>, and Other Gene Fusions/Rearrangements in a Romanian Cohort. [PDF]

Cancers (Basel)
Cohn Vizitiu EA, Tataru E, Csutak O.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Is Ti-Coated PEEK Superior to PEEK for Lumbar and Cervical Fusion Procedures? A Systematic Review and Meta-Analysis. [PDF]

J Clin Med
Kincaid J, Kim RJ, Verma A, Turlip RW, Liu DD, Chauhan D, Dagli MM, Chung RJ, Ahmad HS, Ghenbot Y, Gu B, Yoon JW.   +11 more
europepmc   +1 more source

Fusion Gene Depletion Eliminates Stemness and Induces Bidirectional Differentiation of Acute Myeloid Leukemia [PDF]

Polina K. Derevyanko, Laura E. Swart, L. Daniel Mata Casimiro, Anita van Oort, Manisha du Plessis, Luca van den Brink, C. Michel Zwaan, Anja Krippner‐Heidenreich, Constanze Bonifer, Raymond M. Schiffelers, Josef Vormoor, Sophie G. Kellaway, Olaf Heidenreich   +12 more
openalex   +1 more source

The Associations Between Chronic Active Lesions and White Matter Disease: A 7 Tesla Imaging Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The relationship between paramagnetic rim lesions (PRLs) and surrounding normally appearing white matter (NAWM) disease, potentially contributory to the associations seen between PRLs and clinical impairment, is underexplored. Objectives To assess whether PRLs correlate with a greater degree of NAWM injury in early MS.
Ellie McCluey, Ahmad A. Toubasi, Jiacheng Wang, Habeeb F. Kazimuddin, Taegan Vinarsky, Caroline Gheen, Carynn Koch, Zachery Rohm, Bryan Hernandez, Margareta A. Clarke, Rachael Cheek, Rozita Khalili, Chaoyang Jin, Victoria Lim, John Kramer, Junzhong Xu, Ipek Oguz, Francesca Bagnato   +17 more
wiley   +1 more source