Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
The Application of Biologic and Synthetic Bone Grafts in Scoliosis Surgery: A Scoping Review of Emerging Technologies. [PDF]
Trygonis N, Daskalakis II, Tsagkaris C.
europepmc +1 more source
A Method of Spinal Fusion by Arthrodesis and Iliac Bone Grafts [PDF]
Michele Amata, Terri Harper
openalex +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
The molecular mechanisms of mitochondrial dynamics and mitophagy and their complex association with cancer drug resistance. [PDF]
Zhao Z, Ren Y, Yuan M, Liu G, Sun J.
europepmc +1 more source
Sexual Cell Fusions and Vegetative Nuclear Divisions in the Rusts
Edgar W. Olive
openalex +2 more sources
Microwave Interferometer Measurements for the Determination of Plasma Density Profiles in Controlled Fusion Experiments [PDF]
C. B. Wharton, Donald M. Slager
openalex +1 more source
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Epithelial fusion is mediated by a partial epithelial-mesenchymal transition. [PDF]
Tamilkumar VN +2 more
europepmc +1 more source
The Associations Between Chronic Active Lesions and White Matter Disease: A 7 Tesla Imaging Study
ABSTRACT Background The relationship between paramagnetic rim lesions (PRLs) and surrounding normally appearing white matter (NAWM) disease, potentially contributory to the associations seen between PRLs and clinical impairment, is underexplored. Objectives To assess whether PRLs correlate with a greater degree of NAWM injury in early MS.
Ellie McCluey +17 more
wiley +1 more source

