Results 161 to 170 of about 928,726 (300)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

High Velocity Nasal Insufflation as an Adjunct Treatment for Patient Rewarming in Accidental Hypothermia. [PDF]

Clin Case Rep
Wooldridge MG, Gregorie WD, Hawkins CA, Whittle JS.   +3 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Liquid metals power advanced nuclear energy systems. [PDF]

Innovation (Camb)
Zhang L, Deng C, Ji X, Liu X.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

First achievement of high-confinement mode in proton-boron plasmas. [PDF]

Innovation (Camb)
Wang Y, Shi Y, Guo D, Zhao Y, Yang G, Wang A, Li H, Song S, Yuan Y, Zhang X, Gu X, Zhang C, Li J, Li S, Tao R, Huang X, Zhang Y, Wang Z, Xie Q, Li L, Han L, Zhao X, Xie H, Song X, Dong J, Peng YM, Liang Y, Liu M, EXL-50U Team.   +28 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Estimating the Post-Mortem Interval Under Extreme Heat Environments: A Climate-Adaptive Case Series Based on Artificial Intelligence-Supported Diagnostics. [PDF]

Diagnostics (Basel)
Sessa F, Grippaldi C, Esposito M, Gutierrez CA, Dervišević E, Ulas E, Ministeri F, Mauro LD, Bolcato M, Pomara C, Salerno M.   +10 more
europepmc   +1 more source

Blanket Technology for the Fusion Reactor

, 2016
openaire   +3 more sources

Low-neutron-fluence fusion-blanket dosimetry experiment

, 1980
There is currently a program of integral experiments at the Idaho National Engineering Laboratory (INEL) directed toward evaluating the use of dosimeter materials and techniques in characterizing the neutron fields inside fusion-blanket assemblies.
Rogers, J. W., Harker, Y. D., Novick, V. J., Tsang, F. Y., Greenwood, R. C., Nigg, D. W.   +5 more
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