Results 201 to 210 of about 42,805 (305)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

A multi-scale microstructure to address the strength-ductility trade off in high strength steel for fusion reactors. [PDF]

Nat Commun
Gong P, Kwok TWJ, Wang Y, Dawson H, Goodall R, Dye D, Rainforth WM.   +6 more
europepmc   +1 more source

Thermal design of a fusion breeding blanket

Thermal design of a fusion breeding blanket
国内次期装置の一候補であるスィミングプール型トカマク炉の増殖ブランケットについて熱設計を行なった。ブランケットはチューブインシェルタイプとし、トリチウム増殖領域内Li$_{2}$O温度を400$^{\circ}$C以上、1200$^{\circ}$C以下に保つため、冷却管Li$_{2}$O間にヘリウムガス層を設ける構造とした。又Li$_{2}$O最適ヘリウムギャップおよび最適冷却ピッチを決定した。その結果、ヘリウムギャップは0.75mmとなり、冷却管ピッチは最内列で30mm、最外列で70mmとなった。
openaire  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Evaluating sowing uniformity in hybrid rice using image processing and the OEW-YOLOv8n network. [PDF]

Front Plant Sci
Li Z, Pan Y, Ma X, Lin Y, Wang X, Li H.
europepmc   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Focusing on What Matters: Fine-grained Medical Activity Recognition for Trauma Resuscitation via Actor Tracking. [PDF]

Conf Comput Vis Pattern Recognit Workshops
Zhang W, Li K, Yang S, Yuan S, Marsic I, Sippel GJ, Kim MS, Burd RS.   +7 more
europepmc   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Effects of Body Mass Index on Spondylolisthesis Surgery and Associated Patient-Reported Outcomes: A Retrospective Review. [PDF]

Int J Spine Surg
Garcia R, Odland K, Sembrano J.
europepmc   +1 more source

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source