Results 41 to 50 of about 181,402 (313)
ITER Fusion Device and Its Power Supply System
[Introduction] In order to realize controlled nuclear fusion and solve the future energy problems of mankind, International Thermonuclear Experimental Reactor (ITER) is planning to build a superconducting tokamak device for fusion reaction. [Method] This
Xingguang HU +5 more
doaj +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
In future fusion reactors disruptions must be avoided at all costs. Disruptions due to the density limit (DL) are typically described by the power-independent Greenwald scaling.
P. Manz +3 more
doaj +1 more source
Short- and Medium-Term Power Demand Forecasting with Multiple Factors Based on Multi-Model Fusion [PDF]
Qingqing Ji +8 more
openalex +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The Joint European Torus performed its second deuterium–tritium (DT) campaign at the end of 2021. This unique opportunity was exploited to carry out the first absolute measurement in a magnetic confinement plasma of the total gamma-ray emission from the ...
Giulia Marcer +26 more
doaj +1 more source
Dual-laser powder bed fusion has excellent potential in the preparation of high-performance components due to its ability to suppress defects and control properties during the formation.
Zibin Liu +5 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source

