Results 81 to 90 of about 181,402 (313)

Generation of 10 kT axial magnetic fields using multiple conventional laser beams: A sensitivity study for kJ PW-class laser facilities

Matter and Radiation at Extremes
Strong multi-kilotesla magnetic fields have various applications in high-energy density science and laboratory astrophysics, but they are not readily available. In our previous work [Y. Shi et al., Phys. Rev. Lett.
Jue Xuan Hao, Xiang Tang, Alexey Arefiev, Robert J. Kingham, Ping Zhu, Yin Shi, Jian Zheng   +6 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

A Quasi-Spherical Net Power Fusion Reactor Based on High Temperature Superconducting Magnets [PDF]

, 2023
J.G. Rogers, Andrew A. Egly, F. J. Wessel   +2 more
openalex   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Comparison of CFETR nuclear fusion power plant thermal storage technology

He jishu
BackgroundDue to its pollution-free nature and non consumption of fossil fuels, nuclear fusion is the most ideal future energy source. China is preparing to build a China Fusion Engineering Test Reactor (CFETR) with independent intellectual property ...
LUO Haodong, LIN Yan, LI Bin, XIANG Kui, ZHU Guangtao, ZENG Tao   +5 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Doubling fusion power with volumetric optimization in magnetic confinement fusion devices

Physical Review Research
A technique, volumetric power optimization, is presented for enhancing the power output of magnetic confinement fusion devices. Applied to a tokamak, this approach involves shifting the burning plasma region to a larger plasma volume while introducing ...
J. F. Parisi, J. W. Berkery, A. Sladkomedova, S. Guizzo, M. R. Hardman, J. R. Ball, A. O. Nelson, S. M. Kaye, M. Anastopoulos-Tzanis, S. A. M. McNamara, J. Dominski, S. Janhunen, M. Romanelli, D. Dickinson, A. Diallo, A. Dnestrovskii, W. Guttenfelder, C. Hansen, O. Myatra, H. R. Wilson   +19 more
doaj   +1 more source

Power Plant and Fusion Chamber Considerations for Fast Ignition [PDF]

, 2006
W.R. Meier, William J. Hogan
openalex   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source