Results 121 to 130 of about 501,769 (342)

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Plasma Ramp-up and Sustainment Scenarios for Tokamak Energy’s Fusion Pilot Plant [PDF]

EPJ Web of Conferences
Tokamak Energy is designing a Fusion Pilot Plant under the US Department of Energy’s Milestone-Based Fusion Development Program. Tokamak Energy’s Fusion Pilot Plant is based on low aspect ratio tokamak with high-temperature superconducting coils ...
Takase Yuichi, Astbury Jack, McNamara Steven, Wilson Chris, Alieva Aleksandra, Lopez Nicolas, Zhang Xin   +6 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Summary of the 29th IAEA Fusion Energy Conference under the topics materials, in-vessel components, next-step machines, and licensing and safety and socio-economic and environment

Nuclear Fusion
This paper represents one half of a set of two, covering the TECHNOLOGY presentations at the Fusion Energy Conference (FEC), held in London, UK, in October 2023.
A. Quadling
doaj   +1 more source

Alloy Design for a Fusion Power Plant

, 2009
Fusion power is generated when hot deuterium and tritium nuclei react, producing alpha particles and 14 MeV neutrons. These neutrons escape the reaction plasma and are absorbed by the surrounding material structure of the plant, transferring the heat of the reaction to an external cooling circuit.
openaire   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Automated machine learning workflows for fusion power plant design

The need to meet increasing global energy demand and also address 2050 net zero targets is placing fusion energy in the spotlight. The authors are investigating the ad- vances in digital technology necessary to deliver a fusion power plant by 2040.
Margetts, Lee; id_orcid, Miao, Zeyuan, Smith, William; id_orcid, Omer, Muhammad, Woolland, Oliver, Barker, Adam   +5 more
core   +1 more source

Analysis of supercritical carbon dioxide Brayton cycles for a DEMO-like fusion power plant [PDF]

, 2020
Fusion energy is a clean, abundant and almost-unlimited power source for a future decarbonised energy market. The progressive disappearance of carbon-based power produced has sparked the necessity of finding reliable energy sources that can complement
Hidalgo Salaverri, Javier
core  

Heating and current drive in STEP: why neutral beam injection is not desirable

Nuclear Fusion
Spherical Tokamak for Energy Production (STEP) is the UK’s prototype fusion power plant programme aiming to demonstrate net electrical output from a spherical tokamak. The plasma scenarios require a completely non-inductive current drive for the flat-top
Thomas Wilson, Mark Henderson, Hana El-Haroun, Anurag Saigiridhari, Emmi Tholerus   +4 more
doaj   +1 more source

Development of yttrium-containing self-passivating tungsten alloys for future fusion power plant

, 2016
Tungsten is a prime material candidate for the first wall of a future fusion reactor. In the case of a loss-of-coolant accident (LOCA) wall temperatures of about 1450 K could be reached lasting about 30–60 days due to nuclear decay heat.
T. Wegener, C. Linsmeier, A. Litnovsky, J. Brinkmann, F. Koch   +4 more
semanticscholar   +1 more source