Results 151 to 160 of about 13,524,575 (343)

High temperature superconductors for fusion at the Swiss Plasma Center

High temperature superconductors (HTS) may become in future an option for the superconducting magnets of commercial fusion plants. At the Swiss Plasma Center (SPC) the R&D activity toward HTS high current, high field cables suitable for fusion magnets ...
Bykovsky, N., Uglietti, D., Wesche, R., Bruzzone, P. G   +3 more
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Experimental study on deuterium–deuterium thermonuclear fusion with interface confinement

Friction
Nuclear fusion is recognized as the energy of the future, and considerable effort and capital have been put into the research of controlled nuclear fusion in the past decades.
Darong Chen, Liang Jiang, Shuai Chen, Bao Wang, Dangguo Li, Peng Liang   +5 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

High-Power Mid-Infrared Supercontinuum Light Source Based on High-Quality Fusion of Large-Diameter Silica Fiber and Fluorotellurite Fiber

IEEE Photonics Journal
Mid-infrared supercontinuum (MIR-SC) light sources have garnered significant attention in fields such as material detection and national defence. Currently, mid-infrared lasers suffer from issues including low output power, a narrow spectral range, and a
Xuan Wang, Ying Yang, Chuanfei Yao, Jichen Pan, Yamin Liu, Xuelian Yang, Pingxue Li   +6 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Accelerator based fusion reactor with magnetic mirror

Nuclear Fusion
We consider an implementation of the novel accelerator-based fusion reactor scheme using a setup in which ion and electron beams are injected into the end openings of an axisymmetric magnetic mirror.
Keh-Fei Liu
doaj   +1 more source