Results 41 to 50 of about 1,021,734 (270)
Proceedings of the 11th ACM SIGPLAN International Workshop on Libraries, Languages and Compilers for Array ProgrammingMost efficient state-vector quantum simulation frameworks are imperative. They work by having circuit gates operate on the global state vector in sequence and with each gate operation accessing and updating, in parallel, all (or large subsets of) the elements of the state vector.
Martin Elsman, Troels Henriksen
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Chinese Medical Journal, 2008 Splenogonadal fusion (SGF) is a rare congenital non-malignant anomaly characterized by fusion of splenic tissue to the gonad, and can be continuous or discontinuous. Very few cases have been diagnosed preoperatively, and many patients who present with testicular swelling undergo unnecessary orchiectomy under the suspicion of testicular neoplasm.
Xiao-cao, Shen +4 more
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Revista de Economía Mundial, 2017 Este artículo estudia los determinantes de la IED en América Latina desde una perspectiva novedosa. Demuestra que los denominados efectos de transvase y de confianza, definidos a partir de la posición que cada país ocupa en la red mundial de fusiones y ...
Pablo Galaso +3 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Medición de los beneficios netos en las combinaciones de negocios
Revista de Ciencias Economicas, 2009 Las fusiones y adquisiciones crecieron un 20% anual entre el año 1990 y el 2000, con transacciones que superaron los US $1.000 billones entre 1998 y el 2000 (Andre, 2004). Dado el alcance de las inversiones en combinaciones de negocios, es de esperar que
Nadia Ugalde Binda
doaj