Results 181 to 190 of about 2,692,334 (290)

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Optimistic people are all alike: Shared neural representations supporting episodic future thinking among optimistic individuals. [PDF]

Proc Natl Acad Sci U S A
Yanagisawa K, Nakai R, Asano K, Kashima ES, Sugiura H, Abe N.   +5 more
europepmc   +1 more source

Deficits in episodic future thinking following acute alcohol consumption. [PDF]

Psychopharmacology (Berl), 2022
Elliott M, Terrett G, Curran HV, De Bono N, Rendell PG, Henry JD.   +5 more
europepmc   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Validation and Application of Functions of Future Thinking Scale in Chinese Adults. [PDF]

Psych J
Liu L, Dai L, Wang Y.
europepmc   +1 more source

Episodic future thinking predicts differences in delay discounting: The mediating role of hippocampal structure. [PDF]

Front Psychol, 2022
Guo Y, Wu H, Li Z, Zhao L, Feng T.
europepmc   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

The Influence of Episodic Future Thinking on Prospective Memory in Older Adults. [PDF]

Behav Sci (Basel)
Ma Z, Zhang X.
europepmc   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

What's in a cue?: Using natural language processing to quantify content characteristics of episodic future thinking in the context of overweight and obesity. [PDF]

Health Psychol Behav Med
Downey H, Xu S, Ahmadi S, Shah A, Brown JM, Bickel WK, Epstein LH, Tegge AN, Fox EA, Stein JS.   +9 more
europepmc   +1 more source