Results 111 to 120 of about 1,411,678 (294)
WORK STRATEGY TO MADE AN OUTLINE ASSEMBLY DESIGN
Journal of Industrial Design and Engineering Graphics, 2006 In this paper are presented a detailed study on an existent assembly, used in a new work. Learning stages showed in this project offer to students, futures design engineers, a solid base to correct graphic achievement in assembly and component parts ...
LIHTEŢCHI Ioan
doaj
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Teasing Paradoxes to Explore Transformative Futures of Peace [PDF]
This paper discusses the outcome of a methodologically innovative foresight exercise. A Futures Clinique was conducted to address paradoxes of peace. For the purpose, a novel method of p'aradox probing' was launched where paradoxes are employed as tools ...
Heinonen, Sirkka +3 more
core +1 more source
Towards meeting futures’ educational needs: a case study of CERN IdeaSquare planet
Cogent EducationWith the future being increasingly perceived as uncertain, education must develop skills to foster sustainability and responsibility in unpredictable circumstances.
L. Valtonen +8 more
doaj +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Environmental Research LettersThere is a growing call for transformations to remain within safe and just Earth system boundaries. Coherent visions of desired futures can help motivate and orient such transformations towards Sustainability, but the nature of these transformed futures ...
Silvana Juri +9 more
doaj +1 more source
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Constructing futures: Industry leaders and futures thinking in construction
Australasian Journal of Construction Economics and Building, 2011 Jan Bröchner
doaj +3 more sources
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source