Results 151 to 160 of about 1,411,678 (294)

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Paradigms and Possibilities of Futures-Thinking Within Sustainability Education

Full Text DissertationSustainability has an inherent focus on the future, and because of that, futures-thinking has been proposed as a key competence that sustainability education students and change makers should have and develop.
Lloyd, Deanna
core  

Why and how the humanities matter for sustainability transformations: a humanities-sustainability science bridging perspective. [PDF]

Humanit Soc Sci Commun
Horcea-Milcu AI, Bodden T, Böhnert M, Chacón Pino M, Komorowska A, Reszke P, Schrott A.   +6 more
europepmc   +1 more source

Design and evaluation of FEBS Education and Training Academy module – Integrating generative artificial intelligence into life‐science education

FEBS Open Bio, EarlyView.
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley   +1 more source

Global Water Futures Briefing Book 2024 [PDF]

Second edition of GWF program briefing book, including updates from project annual reports submitted in 2023.Canada First Research Excellence FundNon-Peer ReviewedIn 2016, with initial funding through the Canada First Research Excellence Fund, the Global
Global Water Futures
core  

Consensus-Dominant Futures in Nursing: A Co-Citation and Co-Word Science-Mapping Analysis of Future-Framed Scholarship (1990-2025). [PDF]

Nurs Res Pract
Borromeo AS, Lerma ERM, Bote DS, Cabungcal MM, Wider W.   +4 more
europepmc   +1 more source

GBS‐MeDIP: A method for the simultaneous identification of genetic and epigenetic variants in tumors

FEBS Open Bio, EarlyView.
GBS‐MeDIP combines DNA sequencing with enrichment of methylated DNA to profile genetic and epigenetic variation in the same reduced genomic fraction. Applied to gastric cancer and parathyroid tumors, it identifies sequence variants, copy number changes, and differentially methylated regions together, helping distinguish true epigenetic changes from ...
Fábio Pértille, Shiva Rezaei, Julia Uffenorde, Oliver Gimm, Mohammad Ali Hosseinpour Feizi, Luiz Lehmann Coutinho, Carlos Guerrero‐Bosagna   +6 more
wiley   +1 more source

Using climax thinking to understand psychological drivers of attitudes towards two coastal climate adaptations around the hypertidal Bay of Fundy. [PDF]

Anthr Coasts
Howard S, McWherter B, Akerlof KL, Sherren K.   +3 more
europepmc   +1 more source

Humans That Think: A Future Trialogue.

AI Mag., 1983
We can expect, then, a conference such as this in fifty years ( a hundred years, no need to frame it precisely) to feature as its centerpiece a panel discussion among computers on the fascinating topic of whether humans can really be said to think. Picture three computers, named for no particular reason, Edward, Marvin and Seymour, debating before a ...
openaire   +2 more sources

Potential effect of human chorionic gonadotropin‐induced extracellular vesicle RNAs on mouse ovarian granulosa cells

FEBS Open Bio, EarlyView.
To mimic the LH action in the ovary, granulosa‐cell and mouse models were stimulated by hCG, which changed RNA profiles within extracellular vesicles (EVs), and potentially hCG‐responsive EV RNAs increased the number of recipient ovarian cells. EV‐associated RNAs are potential intermediaries of hCG signaling.
Natchanok Puangjit, Nobuhiko Takahashi, Yuki Maruyama, Shota Mayama, Katsueki Ogiwara, Chika Fujimori, Atsushi P. Kimura   +6 more
wiley   +1 more source