Results 71 to 80 of about 1,411,678 (294)
Cubic Journal, 2023 As humans we are urged to imagine and realise radically different, more desirable, and most importantly more sustainable futures (Hulme 2020; Pereira et al. 2019).
Rike Neuhoff
doaj
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Juvenile probation officers call for a new response to teen drug and alcohol use and dependency [PDF]
, 2007 This document is written by juvenile justice professionals for juvenile justice professionals. It is also written for our justice system partners, treatment providers, family service agencies, policy makers, and community leaders who have a stake in the ...
Reclaiming Futures Treatment Fellowship
core
Early adolescents’ visions of the future: towards hopeful and sustainable futures?
Frontiers in EducationEducation for Sustainable Development (ESD) particularly emphasises developing future-thinking competencies. Nevertheless, this line of thinking still represents a challenge for younger students, who tend to be left behind when deciding and visualising ...
Andrea Corres +3 more
doaj +1 more source
Global Knowledge Futures: Articulating the Emergence of a New Meta-level Field [PDF]
Integral Review, 2013 In this paper I articulate a new meta-level field of studies that I call global knowledge futures—a field through which other emerging transdisciplinary fields can be integrated to cohere knowledge at a higher level.
Jennifer M. Gidley
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Utopian thinking and the intercultural co-creation of urban futures
In_Bo, 2016 As cities face environmental and social pressures related to climate change, they require rapid transformation. Global environmental and social systems are stretched under the strain of highly consumptive middle class lifestyles, particularly in North ...
Maged Senbel
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source