Mepce Restrains Ferroptosis in Prostate Cancer Through 7SK–P‐TEFb Pause Control
Genome‐wide CRISPR screening identifies MEPCE as a pause‐control regulator that restrains ferroptosis in prostate cancer. MEPCE loss releases P‐TEFb/CDK9 from 7SK snRNP control, enhances RNAPII Ser2 phosphorylation, and accelerates NRF2‐HMOX1‐driven labile iron accumulation and lipid peroxidation, revealing a transcriptional kinetic gate that lowers ...
Tongtong Zhang +9 more
wiley +1 more source
Fuzzy topological analysis of fuzzy Helm graphs with applications to protein interaction networks. [PDF]
Mufti ZS +3 more
europepmc +1 more source
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou +18 more
wiley +1 more source
Artificial neuro-fuzzy intelligence for dynamic tracking and prediction of HIV prevalence and new infections among individuals aged 15 to 49 years in Uganda: Computational national-level models. [PDF]
Abdalla EAH +9 more
europepmc +1 more source
Vision begins not with images but with change: the retina fires only when something moves, handing the brain a stream of spikes. A neuromorphic imaging system adopts the same strategy—an event sensor that sees like the retina, a spiking network that thinks like the brain—to track and reconstruct fully randomly moving targets through tissue (phantom ...
Ning Zhang, Arto Nurmikko
wiley +1 more source
Neuro-fuzzy systems in internet of medical things: a systematic review on applications, taxonomy, challenges and open issues. [PDF]
Chilipa R, Nyirenda C.
europepmc +1 more source
Neuromorphic Devices and Computing for Sensing, Memory, and Control
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu +2 more
wiley +1 more source
Evaluating Japanese language learning strategies through learner and expert perspectives: a fuzzy multi-criteria decision-making approach. [PDF]
Liao L, Zhou Q, Sato N.
europepmc +1 more source
Low N/P cells enable controllable lithium plating, allowing the lithium plating degree (DLi) to be quantified and linked to thermal safety. Pressure signals during calibration provide a non‐destructive route to diagnose DLi, while thermal response tests define safety levels and management strategies. The framework remains applicable in commercial 12 Ah
Haonan Liu +10 more
wiley +1 more source
An innovative quantum-fuzzy paradigm for time- and context-sensitive membership: Quantive logic. [PDF]
Yerlikaya MA +4 more
europepmc +1 more source

